Evidence map›Paper›PMID 35948873›Full record

Trial reportBMC nephrology2022

Exploring mHealth potential to improve kidney function: secondary analysis of a randomized trial of diabetes self-care in diverse adults.

McKenzie K Roddy, Lindsay S Mayberry, Devika Nair, Kerri L Cavanaugh

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02409329 (Improving Medication Adherence Among Underserved Patients With Type 2 Diabetes), which is not on this map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02409329 nacompletednot on this map

Improving Medication Adherence Among Underserved Patients With Type 2 Diabetes

TypeinterventionalSponsorVanderbilt University Medical CenterRan2016 to 2019Enrolled512ConditionsDiabetes Mellitus, Type 2ArmsREACH, Helpline and A1c results, REACH + FAMS
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Education programmes for people with chronic kidney disease and diabetes.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

McKenzie K RoddyQuality Scholars, VA Tennessee Valley Healthcare System, Nashville, TN, USA.
Lindsay S MayberryDivision of General Internal Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Devika NairDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kerri L CavanaughDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. kerri.cavanaugh@vanderbilt.edu.
Vanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · US

Funding

Vanderbilt O'Brien Kidney Center - Core D - Clinical and Translational CoreP30DK114809 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FOGO, AGNES B. · 2017 to 2021
$5.9M
Improving Medication Adherence among Underserved Patients with Type 2 DiabetesR01DK100694 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MAYBERRY, LINDSAY S. · 2014 to 2018
$3.3M
Learning Health System Scholar Program at VanderbiltK12HS026395 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ROTHMAN, RUSSELL L., ROUMIE, CHRISTIANNE L. · 2018 to 2022
$2.7M
AHRQ HHS K12 HS026395NIDDK NIH HHS P30 DK114809NIDDK NIH HHS R01 DK100694
6 · The paper itself

Abstract

backgroundMany individuals living with chronic kidney disease (CKD) have comorbid Type 2 diabetes (T2D). We sought to explore if efficacious interventions that improve glycemic control may also have potential to reduce CKD progression.

methodsREACH is a text message-delivered self-management support intervention, which focused on medication adherence, diet, and exercise that significantly improved glycemic control in N = 506 patients with T2D. Using data from the trial, we characterized kidney health in the full sample and explored the intervention's effect on change in estimated glomerular filtration rate (eGFR) at 12 months in a subsample of N=271 patients with eGFR data.

resultsIn a diverse sample with respect to race/ethnicity and socioeconomic status, 37.2% had presence of mild or heavy proteinuria and/or an eGFR < 60 mL/min/1.73 m

conclusionsFuture research should examine whether diabetes directed self-management support reduces CKD progression in ethnically diverse individuals with albuminuria. In highly comorbid populations, such as T2D and CKD, text-based support can be further tailored according to individuals' multimorbid disease self-management needs and is readily scalable for individuals with limited resources.

trial registrationThis study was registered with ClinicalTrials.gov ( NCT02409329 ).

Indexed as

Diabetes Mellitus, Type 2Renal Insufficiency, ChronicTelemedicineAdultGlomerular Filtration RateHumansKidneyProteinuriaSelf CareChronic kidney disease (CKD)mHealthType 2 diabetes (T2D)

Identifiers

PMID35948873
PMCPMC9364602
OpenAlexW4290988534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.