Evidence map›Paper›PMID 35948855›Full record

ArticleVeterinary research communications2022

Phylogenetic and Multiple-Locus Variable number tandem repeat analysis of Mycobacterium avium subsp. paratuberculosis isolates from Argentina.

Brenda Vasini, Pablo Farace, Amadio Ariel, Karina Cirone, Laura Mendez, Claudia Morsella, Pablo Fresia, Gregorio Iraola, Andrea Gioffré, Fernando Paolicchi

Abstract read
PubMed Publisher
In one paragraph

Article in Veterinary research communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. East AsianJournal of veterinary science · 2026
    Article
  2. Article
  3. Molecular Diversity ofAnimals : an open access journal from MDPI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 5 countries.

Brenda VasiniLaboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina. vasinibrenda@gmail.com.ORCID http://orcid.org/0000-0002-5271-3120
Pablo FaraceConsejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Buenos Aires, Argentina.
Amadio ArielConsejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Buenos Aires, Argentina.
Karina CironeLaboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina.
Laura MendezLaboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina.
Claudia MorsellaLaboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina.
Pablo FresiaMicrobial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay.
Gregorio IraolaMicrobial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay.
Andrea Gioffré *Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Buenos Aires, Argentina.
Fernando Paolicchi *Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina.
National University of Mar del Plata · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARInstitut Pasteur de Montevideo · UYUniversidad Mayor · CL

Funding

ANPCyT PICT2015-1541Consejo Nacional de Innovación, Ciencia y Tecnología PIP11220150100316COInstituto Nacional de Tecnología Agropecuaria project2019-PD-E5I103-001
6 · The paper itself

Abstract

Paratuberculosis is a worldwide chronic enteric disease of ruminants, caused by Mycobacterium avium subsp. paratuberculosis (MAP). While MAP has been widely investigated all around the world, little is known about the different strains that circulate in each country. This study describes the genetic diversity of MAP isolates from different bovine and deer herds from Argentina, analyzed by Multiple-Locus Variable number tandem repeat Analysis (MLVA), as well as the phylogenetic relatedness between geographically distant isolates through Whole Genome Sequencing (WGS) and core-genome analysis. A total of 90 MAP isolates were analyzed. The results showed seven different MLVA genotypes, with almost 75% of them belonging to pattern INMV 1, described in all the herds studied. WGS results suggested the presence of a common INMV 1 strain circulating throughout the country. Our results allow confirming the coexistence of different strains in time and space and the mixed infections identified in some animals. These observations suggest the absence of animal monitoring prior to introduction to the herds and the need for a control program in the country. This study represents the first to report WGS of MAP strains in Argentina.

Indexed as

Cattle DiseasesDeerMycobacterium avium subsp. paratuberculosisAnimalsArgentinaCattleMinisatellite RepeatsPhylogenyMLVAMycobacteriumRuminantsWGS

Identifiers

PMID35948855
OpenAlexW4291020346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.