Evidence map›Paper›PMID 35948641›Full record

ArticleNature2022

The retroelement Lx9 puts a brake on the immune response to virus infection.

Nenad Bartonicek, Romain Rouet, Joanna Warren, Claudia Loetsch, Gabriela Santos Rodriguez, Stacey Walters, Francis Lin, David Zahra, James Blackburn, Jillian M Hammond and 13 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 2 institutions in 1 country.

Nenad BartonicekThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Romain RouetThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-4210-9613
Joanna WarrenThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Claudia LoetschThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Gabriela Santos RodriguezThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Stacey WaltersThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Francis LinThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
David ZahraThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
James BlackburnThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0001-5216-8815
Jillian M HammondThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-4045-4571
Andre L M ReisThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-7300-1157
Ira W DevesonThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-3861-0472
Nathan ZammitThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-3694-2951
Mahdi ZeraatiSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, UNSW Sydney, Sydney, New South Wales, Australia.
Shane GreyThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Daniel ChristThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-7313-3977
John S MattickThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-7680-7527
Tatyana ChtanovaThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Robert BrinkThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Marcel E DingerSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, UNSW Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-4423-934X
Robert J WeatherittThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Jonathan SprentThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
Cecile KingThe Garvan Institute of Medical Research, Sydney, New South Wales, Australia. c.king@unsw.edu.au.
Garvan Institute of Medical Research · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The notion that mobile units of nucleic acid known as transposable elements can operate as genomic controlling elements was put forward over six decades ago

Indexed as

DNA Transposable ElementsHost Microbial InteractionsImmunityRetroelementsVirus DiseasesAnimalsCRISPR-Cas SystemsEvolution, MolecularMiceRegulatory Sequences, Nucleic AcidRNA, UntranslatedDNA Transposable ElementsRetroelementsRNA, Untranslated

Identifiers

PMID35948641
OpenAlexW4291020498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.