ArticleAnnals of dermatology2022
Impairment of Quality of Life and Mental Health Status in Adult-Onset Atopic Dermatitis.
Article in Annals of dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Is Atopic Dermatitis Associated with Systemic Metabolic Disturbances? A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Characteristics, Disease Burden and Healthcare Resource Use of Moderate and Severe Atopic Dermatitis in Australia.The Australasian journal of dermatology · 2025Article
- Impact of the COVID-19 pandemic waves on adults with moderate-to-severe atopic dermatitis in the Dutch general population: a population-based longitudinal cohort study.Frontiers in public health · 2025Article
- Adult patients with alopecia areata report a significantly better medication adherence compared to those with atopic dermatitis: Results from a large cross-sectional cohort study.JAAD international · 2024Article
- Do Psoriasis and Atopic Dermatitis Affect Memory, Attention, Stress and Emotions?Brain sciences · 2024Article
- AtopyRegAmerican journal of clinical dermatology · 2024Observational
- Anti-Inflammatory Response in TNFα/IFNγ-Induced HaCaT Keratinocytes and Probiotic Properties ofJournal of microbiology and biotechnology · 2023Article
- Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in Korea.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with atopic dermatitis (AD) have an impaired quality of life (QoL). To our knowledge, impairments in mental health status and health-related QoL (HRQoL) have not yet been evaluated in adult-onset and child-onset AD in a large-scale study.
objectiveThis study compared the mental health status and HRQoL (using the EuroQoL [EQ] five-dimensional [5D] questionnaire) in child-onset AD and adult-onset AD to those in normal controls.
methodsWe used nationwide, population-based, cross-sectional data from the Korean National Health and Nutrition Examination Survey conducted from 2008 to 2013. We performed multiple logistic regression analyses with adjustments for age, sex, body mass index, income, education level, drinking status, current smoking, regular exercise, diabetes mellitus, hypertension, and dyslipidemia, and analyzed odds ratios (OR) for factors associated with impaired QoL.
resultsThe OR for strong psychological stress, depressed mood, and suicidal ideation were significantly increased in adult-onset AD patients compared to in normal controls. In addition, the OR (95% confidence interval [CI]) values for the EQ-5D questionnaire responses (for physical activity, self-control, daily activities, pain/discomfort, and anxiety/depression) were significantly high in adult-onset AD compared to in normal controls after adjustments for covariates. However, patients with child-onset AD showed a significantly increased OR (95% CI) only for problems in pain/discomfort in the EQ-5D questionnaire.
conclusionAdult-onset AD patients suffer from impaired HRQoL and significant mental problems compared to normal controls. Dermatologists should focus not only on the clinical phenotype but also patients' psychological health status to ensure a better treatment outcome.
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