Evidence map›Paper›PMID 35947540›Full record

ArticlePloS one2022

Sex differences in rates of permanent pacemaker implantation and in-hospital complications: A statewide cohort study of over 7 million persons from 2009-2018.

Vijayatubini Vijayarajan, Leonard Kritharides, David Brieger, Yeu-Yao Cheng, Vincent Chow, Austin Chin Chwan Ng

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Article
  10. A Comprehensive Review of Catheter-Related Thrombosis.Journal of clinical medicine · 2024
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Vijayatubini VijayarajanDepartment of Cardiology, Concord Hospital, The University of Sydney, Concord, NSW, Australia.ORCID 0000-0002-1654-1210
Leonard KritharidesDepartment of Cardiology, Concord Hospital, The University of Sydney, Concord, NSW, Australia.
David BriegerDepartment of Cardiology, Concord Hospital, The University of Sydney, Concord, NSW, Australia.
Yeu-Yao ChengDepartment of Cardiology, Concord Hospital, The University of Sydney, Concord, NSW, Australia.
Vincent ChowDepartment of Cardiology, Concord Hospital, The University of Sydney, Concord, NSW, Australia.
Austin Chin Chwan NgDepartment of Cardiology, Concord Hospital, The University of Sydney, Concord, NSW, Australia.ORCID 0000-0002-1317-876X
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether a bias exists in the implantation of permanent pacemakers (PPI) and complications according to sex and age in the Australian population is unclear. HYPOTHESIS: Population rate of PPI and its complications differed between men and women.

methodsWe examined the prevalence of PPI from January-2009 to December-2018 from datasets held by the New South Wales (NSW) Centre-for-Health-Record-Linkage, including patient's characteristics and in-hospital complications. All analysis was stratified by sex and age by decade.

resultsA total of 28,714 admissions involved PPI (40% women). The mean PPI rate (±standard-deviation) and median age (interquartile range) was 2,871±242 per-annum and 80yrs (73-86yrs), respectively. At the same time-period, the mean NSW population size was 7,487,393±315,505 persons (50% women; n = 3,773,756±334,912). The mean annual age-adjusted rate of PPI was 125.5±11.6 per-100,000-men, compared to 63.4±14.3 per-100,000-women (P<0.01). The mean annual rate of PPI increased from 2009-2017 by 0.9±3.3% in men, compared to 0.4±4.4% in women (P<0.01) suggesting a widening disparity. Total non-fatal in-hospital complications was higher in women compared to men (8.2% vs 6.6%, P<0.01), and this persisted throughout study period even after adjusting for multiple covariates. Overall, in-hospital mortality was low (0.73%) and similar between sexes.

conclusionIn a statewide Australian population exceeding 7 million, PPI rates were consistently nearly two-fold higher for men compared to women over 10-years, with an apparently widening disparity, that was not explained by age. Overall complication rates were higher in women. Future studies should examine the aetiology behind this disparity in PPI rates, as well as its complications.

Indexed as

Pacemaker, ArtificialSex CharacteristicsAustraliaCohort StudiesFemaleHospitalsHumansMaleRetrospective StudiesRisk Factors

Identifiers

PMID35947540
PMCPMC9365143
OpenAlexW4291284184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.