Evidence map›Paper›PMID 35947346›Full record

ArticleHead and neck pathology2022

Basal Cell Adenoma and Basal Cell Adenocarcinoma: a 50-year Experience From a Single Institution.

Miguel Rito, Susana Esteves, Isabel Fonseca

Open access · greenAbstract read
In one paragraph

Article in Head and neck pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Miguel RitoServiço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa, R. Prof. Lima Basto, 1099-023, Lisbon, Portugal. miguelrito@gmail.com.ORCID http://orcid.org/0000-0002-0226-5905
Susana EstevesUnidade de Investigação Clínica, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal.
Isabel FonsecaServiço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa, R. Prof. Lima Basto, 1099-023, Lisbon, Portugal.
University of Lisbon · PTIPO Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBasal cell adenoma (BCA) and adenocarcinoma (BCAd) are two of the least frequent salivary gland tumors. We describe the largest series of these neoplasms, spanning over a period of 50 years (1970-2020), diagnosed and treated in a single Institution.

methodsSixty-eight cases were identified. Clinical and pathological data were collected and correlated with outcome.

resultsForty-one BCA and 27 BCAd were identified. BCA cases had almost pristine prognosis, with only a relapse in a tumor inadequately excised. Ten patients with BCAd developed metastases, and 14 died from the disease. The 2-year and 5-year survival was of 76% and 42%.

conclusionsThe importance of adequate excision is reinforced in BCA, with no recurrences occurring when margins were negative. Contrary to previous reports, BCAd was not associated with a good prognosis. A better understanding of the genetics of these neoplasms may identify therapeutic options when dealing with inoperable or metastatic disease.

Indexed as

AdenocarcinomaAdenomaSalivary Gland NeoplasmsHumansBasal cell adenocarcinomaBasal cell adenomaCarcinoma ex pleomorphic adenomaHead and neck neoplasmsOtorhinolaryngologic neoplasmsSalivary gland

Identifiers

PMID35947346
PMCPMC9729486
OpenAlexW4295969653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.