Evidence map›Paper›PMID 35947279›Full record

Trial reportInternational urology and nephrology2022

Efficacy of combination therapy with biofeedback and dapoxetine in lifelong premature ejaculation treatment: a prospective randomized study.

Ali Haydar Yılmaz, Ahmet Emre Cinislioglu, Saban Oğuz Demirdöğen, Fatih Kursat Yılmazel, Emre Sam, Ibrahim Karabulut, Mahmut Koç, Isa Özbey

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ali Haydar YılmazDepartment of Urology, Bilecik Training and Research Hospital, Bilecik, Turkey. alicerrahcom@yahoo.com.ORCID http://orcid.org/0000-0001-5797-0655
Ahmet Emre CinisliogluUrology, Health Sciences University, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.ORCID http://orcid.org/0000-0002-1037-815X
Saban Oğuz DemirdöğenUrology, Health Sciences University, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.ORCID http://orcid.org/0000-0002-8697-8995
Fatih Kursat YılmazelUrology, Health Sciences University, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.ORCID http://orcid.org/0000-0001-8744-5317
Emre SamUrology, Health Sciences University, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.ORCID http://orcid.org/0000-0001-7706-465X
Ibrahim KarabulutUrology, Health Sciences University, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.ORCID http://orcid.org/0000-0001-6766-0191
Mahmut KoçDepartment of Urology, Bilecik Training and Research Hospital, Bilecik, Turkey.
Isa ÖzbeyUrology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.ORCID http://orcid.org/0000-0002-7889-3174
Erzurum Regional Training and Research Hospital · TRBilecik Şeyh Edebali Üniversitesi · TRAtatürk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePremature ejaculation (PE) is a common sexual dysfunction that significantly affects the quality of life of the patient and their partner. We aimed to compare the efficacy and safety of the combination therapy with biofeedback-guided pelvic floor exercise therapy (BFT) and dapoxetine 30 mg.

methodsSixty-five patients diagnosed with lifelong PE were included in the study. Patients were divided into three groups as BFT, dapoxetine 30 mg and a combination of BFT and dapoxetine 30 mg. The patients were compared with the intravaginal ejaculatory latency time (IELT) pre-treatment and post-treatment 1st and 3rd months.

resultsThe mean IELTs of the patients in Group 1 were 40 s in pre-treatment, 115 s at the end of the 4th week and 140 s at the end of the 12th week. The IELT values of the patients in Group 2 were 40 s in pre-treatment, 145 s in the 4th week and 170 s in the 12th week. The IELT values were calculated in Group 3 as 42.5 s in pre-treatment, 185 s in the 4th week and 205 s in the 12th week When the IELT was statistically compared between the groups at 1st and 3rd months, the duration in the combination group was found to increase significantly (p < 0.001).

conclusionCombination therapy with BFT and dapoxetine 30 mg in lifelong PE treatment is a good alternative with a low side effect profile and acceptable continuous efficiency.

Indexed as

Premature EjaculationBenzylaminesBiofeedback, PsychologyEjaculationHumansMaleNaphthalenesProspective StudiesQuality of LifeSelective Serotonin Reuptake InhibitorsTreatment OutcomeBenzylaminesdapoxetineNaphthalenesSelective Serotonin Reuptake InhibitorsBiofeedbackDapoxetineEjaculationPelvik floorPremature

Identifiers

PMID35947279
OpenAlexW4297826842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.