Evidence map›Paper›PMID 35947060›Full record

Observational studyPediatric emergency care2022

Survival Rates After Pediatric Traumatic Out-of-Hospital Cardiac Arrest Suggest an Underappreciated Therapeutic Opportunity.

Maria Lanyi, Jonathan Elmer, Francis X Guyette, Christian Martin-Gill, Arvind Venkat, Owen Traynor, Heather Walker, Kristen Seaman, Patrick M Kochanek, Ericka L Fink

Abstract readObservational Study
In one paragraph

Observational study in Pediatric emergency care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Age-specific considerations in aetiology of paediatric out-of-hospital cardiac arrest.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria LanyiFrom the University of Pittsburgh Medical School.
Jonathan Elmer
Francis X GuyetteDepartment of Emergency Medicine, University of Pittsburgh School of Medicine.
Christian Martin-GillDepartment of Emergency Medicine, University of Pittsburgh School of Medicine.
Arvind VenkatDepartment of Emergency Medicine, Allegheny Health Network.
Owen TraynorDepartment of Emergency Medicine, St Clair Hospital, Pittsburgh.
Heather WalkerDepartment of Emergency Medicine, Excela Health, Greensburg.
Kristen Seaman
Patrick M Kochanek
Ericka L Fink

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Development of Serum, Imaging, and Clinical Biomarker Driven Models to Direct Clinical Management after Pediatric Cardiac ArrestR01NS096714 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINK, ERICKA LINN · 2016 to 2020
$2.6M
Quantitative electroencephalography after cardiac arrestK23NS097629 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ELMER, JONATHAN · 2017 to 2021
$945k
Duration of Hypothermia for Neuroprotection after Pediatric Cardiac ArrestK23NS065132 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINK, ERICKA LINN · 2009 to 2013
$807k
NCATS NIH HHS UL1 TR001857NINDS NIH HHS K23 NS065132NINDS NIH HHS K23 NS097629NINDS NIH HHS R01 NS096714
6 · The paper itself

Abstract

objectivesChildren with traumatic arrests represent almost one third of annual pediatric out-of-hospital cardiac arrests (OHCAs). However, traumatic arrests are often excluded from study populations because survival posttraumatic arrest is thought to be negligible. We hypothesized that children treated and transported by emergency medical services (EMS) personnel after traumatic OHCA would have lower survival compared with children treated after medical OHCA.

methodsWe performed a secondary, observational study of children younger than 18 years treated and transported by 78 EMS agencies in southwestern Pennsylvania after OHCA from 2010 to 2014. Etiology was determined as trauma or medical by EMS services. We analyzed patient, cardiac arrest, and resuscitation characteristics and ascertained vital status using the National Death Index. We used multivariable logistic regression to test the association of etiology with mortality after covariate adjustment.

resultsForty eight of 209 children (23%) had traumatic OHCA. Children with trauma were older than those with medical OHCA (13.2 [3.8-15.9] vs 0.5 [0.2-2.4] years, P < 0.001). Prehospital return of spontaneous circulation frequency for trauma versus medical etiology was similar (90% vs 87%, P = 0.84). Patients with trauma had higher mortality (69% vs 45% P = 0.004).

conclusionsMore than 8 of 10 children with EMS treated and transported OHCA achieved return of spontaneous circulation. Despite lower survival rates than medical OHCA patients, almost one third of children with a traumatic etiology survived throughout the study period. Future research programs warrant inclusion of children with traumatic OHCA to improve outcomes.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestChildHumansLogistic ModelsSurvival Rate

Identifiers

PMID35947060
PMCPMC9427720

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.