Evidence map›Paper›PMID 35946811›Full record

ArticleMicrobiology spectrum2022

Humoral and Cellular Immune Responses to Vector, Mix-and-Match, or mRNA Vaccines against SARS-CoV-2 and the Relationship between the Two Immune Responses.

Minjeong Nam, Seung Gyu Yun, Sang-Wook Kim, Chris Gunwoo Kim, Jae Hyun Cha, Cheonghwa Lee, Seunghyuk Kang, Seul Gi Park, Sun Bean Kim, Ki-Byung Lee and 4 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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  12. Sex-Differential and Non-specific Effects of Vaccines Over the Life Course.Current topics in microbiology and immunology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Minjeong NamDepartment of Laboratory Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0003-3542-3487
Seung Gyu YunDepartment of Laboratory Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0002-9915-9681
Sang-Wook KimGyeryong City Health, Gyeryong-si, Chungcheongnam-do, South Korea.
Chris Gunwoo KimDepartment of Laboratory Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0003-3526-8034
Jae Hyun ChaDepartment of Laboratory Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0003-2503-3469
Cheonghwa LeeDepartment of Laboratory Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0001-8171-5005
Seunghyuk KangDepartment of Laboratory Medicine, Korea University Anam Hospital, Seoul, South Korea.
Seul Gi ParkDepartment of Laboratory Medicine, Korea University Anam Hospital, Seoul, South Korea.
Sun Bean KimDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0002-9983-4392
Ki-Byung LeeDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0001-9106-5528
You-Seung ChungDivision of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0002-6568-0516
Myung-Hyun NamDepartment of Laboratory Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0002-8737-6902
Chang Kyu LeeDepartment of Laboratory Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0001-7528-7833
Yunjung ChoDepartment of Laboratory Medicine, Korea University College of Medicine, Korea University Anam Hospital, Seoul, South Korea.ORCID 0000-0002-6942-8385
Korea University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated how differences in age, sex, or vaccine type can affect humoral and cellular immune responses after vaccination with vector (ChAdOx1 nCoV-19), mix-and-match (first, ChAdOx1 nCoV-19, and second, BNT162b2), or mRNA (BNT162b2 or mRNA-1273) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Venous blood was collected from 573 subjects (vector, 396; mix-and-match, 96; and mRNA, 81) before the first vaccination (

Indexed as

COVID-19Viral VaccinesAntibodies, NeutralizingAntibodies, ViralBNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesFemaleHumansImmunity, CellularMalemRNA VaccinesRNA, MessengerSARS-CoV-2VaccinationVaccines, SyntheticAntibodies, NeutralizingAntibodies, ViralBNT162 VaccineChAdOx1 nCoV-19COVID-19 VaccinesmRNA VaccinesRNA, MessengerVaccines, SyntheticViral Vaccinescellular immune responseshumoral immune responsesmix-and-match vaccinemRNA vaccinevector vaccine

Identifiers

PMID35946811
PMCPMC9431224
OpenAlexW4293900578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.