SynthesisEinstein (Sao Paulo, Brazil)2022
Mechanical thrombectomy for acute ischemic stroke: systematic review and meta-analysis.
Synthesis in Einstein (Sao Paulo, Brazil), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- An umbrella review of systematic reviews and meta-analyses evaluating the efficacy and safety of mechanical thrombectomy for acute ischemic stroke.Annals of medicine and surgery (2012) · 2026Article
- Elevated B-type natriuretic peptide levels as prognostic biomarkers for walking independence in patients with stroke in the post-acute phase.Heart and vessels · 2026Article
- Safety and efficacy of endovascular treatment for pediatric acute ischemic stroke: a systematic review and Meta-analysis.Journal of thrombosis and thrombolysis · 2026Review
- Perioperative Determinants of Functional Outcome and Mortality After Mechanical Thrombectomy Under General Anesthesia.Journal of clinical medicine · 2026Article
- Comprehensive immunological profiling of acute ischemic stroke during mechanical thrombectomy: myeloid cell activation and molecular signatures in blood and thrombus.Frontiers in stroke · 2026Article
- Identification of Differential Proteins in Thrombi of Cardioembolic and Atherothrombotic Etiology in Patients with Ischemic Stroke.International journal of molecular sciences · 2025Article
- Development and validation of a multi-omics hemorrhagic transformation model based on hyperattenuated imaging markers following mechanical thrombectomy.Scientific reports · 2025Article
- The real-life reliability of the modified Rankin scale used in a stroke unit and a rehabilitation ward.Postepy psychiatrii neurologii · 2025Article
- High relative cerebral blood volume is associated with good long term clinical outcomes in acute ischemic stroke: a retrospective cohort study.BMC neurology · 2024Article
- Atrial Fibrillation and Reperfusion Therapy in Acute Ischaemic Stroke Patients: Prevalence and Outcomes-A Comprehensive Systematic Review and Meta-Analysis.Neurology international · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the safety and efficacy of mechanical thrombectomy associated with standard medical treatment compared with standard medical treatment only to treat patients with acute ischemic stroke.
methodsThis was a systematic review and metaanalysis of randomized controlled trials. An electronic search was performed in the following databases: MEDLINE ® /PubMed ® , Cochrane Library (Trials), LILACS/IBECS (via Biblioteca Virtual em Saúde (BVS)) and Embase. Complementary searches were also conducted. The selection of studies and data collection were done by two investigators independently.
resultsThe final analysis included 16 publications related to 15 studies. The mechanical thrombectomy was associated to a reduction in the risk of death of all cause (16.81% versus 20.13%; relative risk of 0.85; p=0.04), improvement in the number of patients with functional independence after 90 days (45.65% versus 27.45%; relative risk of 1.65; p<0.01), and improvement in the rate of revascularization (76.2% versus 33.85%; relative risk of 2.20; p<0.01). There was no significant difference in terms of symptomatic intracranial hemorrhage (4.78% versus 3.88%; relative risk of 1.27; p=0.21).
conclusionMechanical thrombectomy associated with standard medical treatment seem to be safe and effective to treat patients with acute ischemic stroke compared with standard medical treatment only.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.