Evidence map›Paper›PMID 35946455›Full record

ArticleJournal of the American Heart Association2022

Temporal Changes, Patient Characteristics, and Mortality, According to Microbiological Cause of Infective Endocarditis: A Nationwide Study.

Lauge Østergaard, Marianne Voldstedlund, Niels Eske Bruun, Henning Bundgaard, Kasper Iversen, Nana Køber, Jens Jørgen Christensen, Flemming Schønning Rosenvinge, Jens Otto Jarløv, Claus Moser and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Infective endocarditis and post-treatment bacteremia caused by oral microorganisms: a retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Surgery inJournal of clinical medicine · 2025
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Outcomes ofJAC-antimicrobial resistance · 2024
    Article
  18. Article
  19. Enterococcal quorum-controlled protease alters phage infection.bioRxiv : the preprint server for biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Lauge ØstergaardThe Heart Centre, Rigshospitalet University of Copenhagen Copenhagen Denmark.ORCID 0000-0003-3298-1467
Marianne VoldstedlundStatens Serum Institut Copenhagen Denmark.
Niels Eske BruunDepartment of Cardiology Zealand University Hospital Roskilde Denmark.ORCID 0000-0002-5026-9193
Henning BundgaardThe Heart Centre, Rigshospitalet University of Copenhagen Copenhagen Denmark.ORCID 0000-0002-0563-7049
Kasper IversenDepartment of Cardiology Herlev-Gentofte Hospital University of Copenhagen Copenhagen Denmark.ORCID 0000-0003-0504-8487
Nana KøberDepartment of Cardiology Bispebjerg-Frederiksberg Hospital University of Copenhagen Copenhagen Denmark.
Jens Jørgen ChristensenThe Regional Department of Clinical Microbiology Zealand University Hospital Køge and Institute of Clinical Medicine University of Copenhagen Copenhagen Denmark.ORCID 0000-0001-6721-4917
Flemming Schønning RosenvingeDepartment of Clinical Microbiology Odense University Hospital and Research Unit of Clinical Microbiology University of Southern Denmark Odense Denmark.ORCID 0000-0003-2129-328X
Jens Otto JarløvDepartment of Clinical Microbiology Herlev-Gentofte Hospital University of Copenhagen Copenhagen Denmark.
Claus MoserDepartment of Clinical Microbiology Rigshospitalet University of Copenhagen Copenhagen Denmark.
Christian Østergaard AndersenDepartment of Clinical Microbiology Amager-Hvidovre Hospital Copenhagen Denmark.
John CoiaDepartment of Clinical Microbiology Esbjerg Hospital Esbjerg Denmark.ORCID 0000-0002-4966-8453
Ea Sofie MarmolinDepartment of Clinical Microbiology Vejle Hospital Vejle Denmark.
Kirstine K SøgaardDepartment of Clinical Microbiology Aalborg University Hospital Aalborg Denmark.
Lars LemmingDepartment of Clinical Microbiology Aarhus University Hospital Aarhus Denmark.
Lars KøberThe Heart Centre, Rigshospitalet University of Copenhagen Copenhagen Denmark.ORCID 0000-0002-6635-1466
Emil Loldrup FosbølThe Heart Centre, Rigshospitalet University of Copenhagen Copenhagen Denmark.
University of Copenhagen · DKAalborg University Hospital · DKAarhus University Hospital · DKAmager Hospital · DKStatens Serum Institut · DKUniversity of Southern Denmark · DKVejle Sygehus · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Monitoring of microbiological cause of infective endocarditis (IE) remains key in the understanding of IE; however, data from large, unselected cohorts are sparse. We aimed to examine temporal changes, patient characteristics, and in-hospital and long-term mortality, according to microbiological cause in patients with IE from 2010 to 2017. Methods and Results Linking Danish nationwide registries, we identified all patients with first-time IE. In-hospital and long-term mortality rates were assessed according to microbiological cause and compared using multivariable adjusted logistic regression analysis and Cox proportional hazard analysis, respectively. A total of 4123 patients were included.

Indexed as

EndocarditisEndocarditis, BacterialHeart Valve ProsthesisStaphylococcal InfectionsCoagulaseHospital MortalityHumansRetrospective StudiesStaphylococcus aureusCoagulasebloodstream infectioninfective endocarditismicrobiological causenationwide studypopulation study

Identifiers

PMID35946455
PMCPMC9496298
OpenAlexW4292168263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.