Evidence map›Paper›PMID 35946454›Full record

ArticleMolecular medicine reports2022

Puerarin attenuates isoproterenol‑induced myocardial hypertrophy via inhibition of the Wnt/β‑catenin signaling pathway.

Xiaoying Wang, Kai He, Linlin Ma, Lan Wu, Yan Yang, Yanfei Li

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiaoying Wang *Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China.
Kai He *Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China.
Linlin MaCollege of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, P.R. China.
Lan WuCollege of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai 201318, P.R. China.
Yan YangInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201106, P.R. China.
Yanfei LiGraduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China.
Shanghai University of Traditional Chinese Medicine · CNShanghai University of Medicine and Health Sciences · CNShanghai Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial hypertrophy (MH) is an independent risk factor for cardiovascular disease, which in turn lead to arrhythmia or heart failure. Therefore, attention must be paid to formulation of therapeutic strategies for MH. Puerarin is a key bioactive ingredient isolated from

Indexed as

IsoflavonesWnt Signaling PathwayCardiomegalyHumansIsoproterenolRNA, MessengerIsoflavonesIsoproterenolpuerarinRNA, Messengercardiac hypertrophyisoproterenolp65phosphorylation of NF‑κBpuerarinWnt/β‑catenin signaling pathway

Identifiers

PMID35946454
PMCPMC9437969
OpenAlexW4295756391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.