Evidence map›Paper›PMID 35946176›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2022

Animal unit hygienic conditions influence mouse intestinal microbiota and contribute to T-cell-mediated colitis.

Mariana Cázares-Olivera, Dominika Miroszewska, Lili Hu, Jacek Kowalski, Ulla-Marjut Jaakkola, Seppo Salminen, Bin Li, Emrah Yatkin, Zhi Chen

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Mariana Cázares-OliveraFaculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland.ORCID 0000-0003-2371-9889
Dominika MiroszewskaIntercollegiate Faculty of Biotechnology of University of Gdańsk and Medical University of Gdańsk, University of Gdańsk, 80-307 Gdańsk, Poland.
Lili HuFaculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland.
Jacek KowalskiDepartment of Pathomorphology, Medical University of Gdańsk, 80-210 Gdańsk, Poland.
Ulla-Marjut JaakkolaCentral Animal Laboratory, Faculty of Medicine, University of Turku (UTUCAL), 20520 Turku, Finland.
Seppo SalminenFunctional Foods Forum, Faculty of Medicine, University of Turku, 20520 Turku, Finland.
Bin LiShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200085, China.
Emrah YatkinCentral Animal Laboratory, Faculty of Medicine, University of Turku (UTUCAL), 20520 Turku, Finland.
Zhi ChenFaculty of Biochemistry and Molecular Medicine, University of Oulu, 90220 Oulu, Finland.ORCID 0000-0002-4658-7463
Gdańsk Medical University · PLUniversity of Turku · FIUniversity of Oulu · FIShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders of the gastrointestinal tract with worldwide increasing incidence. Recent studies indicate that certain species of intestinal bacteria are strongly associated with IBD. Helper T lymphocytes are not only the key players in mediating host defense against a wide variety of pathogens but also contribute to pathogenesis of many immune-related diseases. Here, using the T cell transfer model of colitis, we observed that the mice maintained in a specific-pathogen free (SPF) unit after receiving naïve CD4

Indexed as

ColitisGastrointestinal MicrobiomeInflammatory Bowel DiseasesAnimalsDisease Models, AnimalMiceMice, Inbred C57BLRNA, Ribosomal, 16SRNA, Ribosomal, 16Shelper T cellshygienic conditionsintestine inflammationMicrobiotaTh17 cells

Identifiers

PMID35946176
PMCPMC9638955
OpenAlexW4297825378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.