Evidence map›Paper›PMID 35946154›Full record

ArticleProceedings. Biological sciences2022

Big brown bats experience slower epigenetic ageing during hibernation.

Isabel R Sullivan, Danielle M Adams, Lucas J S Greville, Paul A Faure, Gerald S Wilkinson

Open access · greenAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Sex differences in DNA methylation in bats.Annals of the New York Academy of Sciences · 2025
    Article
  6. Article
  7. Article
  8. The androgen clock is an epigenetic predictor of long-term male hormone exposure.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Bats as instructive animal models for studying longevity and aging.Annals of the New York Academy of Sciences · 2024
    Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Isabel R SullivanDepartment of Biology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0001-7773-6735
Danielle M AdamsDepartment of Biology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0002-8260-4064
Lucas J S GrevilleDepartment of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada L8S 4K1.ORCID 0000-0002-9921-2972
Paul A FaureDepartment of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada L8S 4K1.ORCID 0000-0001-6221-5718
Gerald S WilkinsonDepartment of Biology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0001-7799-8444
University of Maryland, College Park · USMcMaster University · CATowson University · USUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comparative analyses of bats indicate that hibernation is associated with increased longevity among species. However, it is not yet known if hibernation affects biological ageing of individuals. Here, we use DNA methylation (DNAm) as an epigenetic biomarker of ageing to determine the effect of hibernation on the big brown bat,

Indexed as

AgingChiropteraHibernationAnimalsEpigenesis, GeneticGenome-Wide Association StudyDNA methylationepigenetic clockEptesicus fuscusimmunitylongevitymetabolism

Identifiers

PMID35946154
PMCPMC9364000
OpenAlexW4291019068

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.