Evidence map›Paper›PMID 35945943›Full record

Trial reportPeerJ2022

Randomized feasibility trial of the Scleroderma Patient-centered Intervention Network hand exercise program (SPIN-HAND).

Linda Kwakkenbos, Marie-Eve Carrier, Joep Welling, Kimberly A Turner, Julie Cumin, Mia Pépin, Cornelia van den Ende, Anne A Schouffoer, Marie Hudson, Ward van Breda and 10 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 4 countries.

Linda KwakkenbosRadboud University Nijmegen, Nijmegen, Netherlands.
Marie-Eve CarrierLady Davis Institute of the Jewish General Hospital, Montreal, Canada.
Joep WellingNVLE Dutch patient organization for systemic autoimmune diseases, Utrecht, The Netherlands.
Kimberly A TurnerLady Davis Institute of the Jewish General Hospital, Montreal, Canada.
Julie CuminLady Davis Institute of the Jewish General Hospital, Montreal, Canada.
Mia PépinLady Davis Institute of the Jewish General Hospital, Montreal, Canada.
Cornelia van den EndeSint Maartenskliniek, Nijmegen, The Netherlands.
Anne A SchouffoerLeiden University Medical Center, Leiden, The Netherlands.
Marie HudsonLady Davis Institute of the Jewish General Hospital, Montreal, Canada.
Ward van BredaFaculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands.
Maureen SauveScleroderma Society of Ontario, Hamilton, Ontario, Canada.
Maureen D MayesUniversity of Texas McGovern School of Medicine, Houston, Texas, United States of America.
Vanessa L MalcarneSan Diego State University, San Diego, CA, United States of America.
Warren R NielsonSt. Joseph's Health Care, London, Ontario, Canada.
Christelle NguyenUniversité de Paris, Paris, France.
Isabelle BoutronCentre d'Épidémiologie Clinique, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Hôtel Dieu, Paris, France.
François RannouUniversité de Paris, Paris, France.
Brett D ThombsLady Davis Institute of the Jewish General Hospital, Montreal, Canada.
Luc MouthonService de Médecine Interne, Centre de Référence Maladies Autoimmunes Systémiques Rares d'Ile de France, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
SPIN Investigators
Jewish General Hospital · CAUniversité Paris Cité · FRHôpital Cochin · FRLeiden University Medical Center · NLMultiple Sclerosis Society of Canada · CARadboud University Nijmegen · NLSan Diego State University · USSint Maartenskliniek · NLSt Joseph's Health Care · CAVrije Universiteit Amsterdam · NL

Funding

CIHR PJT-148504CIHR PJT-149073CIHR TR3-119192
6 · The paper itself

Abstract

Purpose: The Scleroderma Patient-centered Intervention Network (SPIN) online hand exercise program (SPIN-HAND), is an online self-help program of hand exercises designed to improve hand function for people with scleroderma. The objective of this feasibility trial was to evaluate aspects of feasibility for conducting a full-scale randomized controlled trial of the SPIN-HAND program. Materials and Methods: The feasibility trial was embedded in the SPIN cohort and utilized the cohort multiple randomized controlled trial (cmRCT) design. In the cmRCT design, at the time of cohort enrollment, cohort participants consent to be assessed for trial eligibility and randomized prior to being informed about trials conducted using the cohort. When trials were conducted in the cohort, participants randomized to the intervention were informed and consented to access the intervention. Participants randomized to control were not informed that they have not received an intervention. All participants eligible and randomized to participate in the trial were included in analyses on an intent-to-treat basis. Cohort participants with a Cochin Hand Function Scale score ≥ 3/90 and an interest in using an online hand-exercise intervention were randomized (1:1 ratio) to be offered as usual care plus the SPIN-HAND Program or usual care for 3 months. User satisfaction was assessed with semi-structured interviews. Results: Of the 40 randomized participants, 24 were allocated to SPIN-HAND and 16 to usual care. Of 24 participants randomized to be offered SPIN-HAND, 15 (63%) consented to use the program. Usage of SPIN-HAND content among the 15 participants who consented to use the program was low; only five (33%) logged in more than twice. Participants found the content relevant and easy to understand (satisfaction rating 8.5/10, Conclusions: Trial methodology functioned as designed, and the SPIN-HAND Program was feasibly delivered; however, the acceptance of the offer and use of program content among accepters were low. Adjustments to information provided to potential participants will be implemented in the full-scale SPIN-HAND trial to attempt to increase offer acceptance.

Indexed as

Behavior TherapyExercise TherapyPatient-Centered CareScleroderma, SystemicFeasibility StudiesHumansResearch DesignTelerehabilitationCohort multiple RCTFeasibility trialInternet interventionOccupational therapyPhysical therapySclerodermaSystemic sclerosisTele-rehabilitation

Identifiers

PMID35945943
PMCPMC9357372
OpenAlexW3041137234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.