ArticleCerebral cortex (New York, N.Y. : 1991)2023
Normative quantitative relaxation atlases for characterization of cortical regions using magnetic resonance fingerprinting.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Mapping Neurodegenerative Changes in Clinically Uncertain Parkinsonian Syndrome Patients Using Fast MR Spin TomogrAphy in Time-Domain (MR-STAT) Relaxometry at 3T.Journal of magnetic resonance imaging : JMRI · 2026Article
- Clinical use and radiological yield of magnetic resonance fingerprinting in epilepsy.Epilepsia · 2026Article
- Utility of MR fingerprinting in differentiating epileptogenic from non-epileptogenic cortical malformations.Journal of the neurological sciences · 2025Article
- Automated Whole-Brain Focal Cortical Dysplasia Detection Using MR Fingerprinting With Deep Learning.Neurology · 2025Article
- Time-efficient, high-resolution 3T whole-brain relaxometry using Cartesian 3D MR Spin TomogrAphy in Time-Domain (MR-STAT) with cerebrospinal fluid suppression.Magnetic resonance in medicine · 2025Article
- Fast whole brain relaxometry with Magnetic Resonance Spin TomogrAphy in Time-domain (MR-STAT) at 3 T: a retrospective cohort study.Magma (New York, N.Y.) · 2025Article
- Multiparametric Characterization of Focal Cortical Dysplasia Using 3D MR Fingerprinting.Annals of neurology · 2024Article
- A Histopathologic Correlation Study Evaluating Glymphatic Function in Brain Tumors by Multiparametric MRI.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024Article
- Article
- High-resolution myelin-water fraction and quantitative relaxation mapping using 3D ViSTa-MR fingerprinting.Magnetic resonance in medicine · 2024Article
- High-resolution myelin-water fraction and quantitative relaxation mapping using 3D ViSTa-MR fingerprinting.ArXiv · 2023Article
- Evaluating whole-brain tissue-property changes in MRI-negative pharmacoresistant focal epilepsies using MR fingerprinting.Epilepsia · 2023Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
Abstract
Quantitative magnetic resonance (MR) has been used to study cyto- and myelo-architecture of the human brain non-invasively. However, analyzing brain cortex using high-resolution quantitative MR acquisition can be challenging to perform using 3T clinical scanners. MR fingerprinting (MRF) is a highly efficient and clinically feasible quantitative MR technique that simultaneously provides T1 and T2 relaxation maps. Using 3D MRF from 40 healthy subjects (mean age = 25.6 ± 4.3 years) scanned on 3T magnetic resonance imaging, we generated whole-brain gyral-based normative MR relaxation atlases and investigated cortical-region-based T1 and T2 variations. Gender and age dependency of T1 and T2 variations were additionally analyzed. The coefficient of variation of T1 and T2 for each cortical-region was 3.5% and 7.3%, respectively, supporting low variability of MRF measurements across subjects. Significant differences in T1 and T2 were identified among 34 brain regions (P < 0.001), lower in the precentral, postcentral, paracentral lobule, transverse temporal, lateral occipital, and cingulate areas, which contain sensorimotor, auditory, visual, and limbic functions. Significant correlations were identified between age and T1 and T2 values. This study established whole-brain MRF T1 and T2 atlases of healthy subjects using a clinical 3T scanner, which can provide a quantitative and region-specific baseline for future brain studies and pathology detection.
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