Evidence map›Paper›PMID 35945636›Full record

ArticleAddiction science & clinical practice2022

Perceptions of buprenorphine barriers and efficacy among nurse practitioners and physician assistants.

Barbara Andraka-Christou, Cory Page, Victoria Schoebel, Jessica Buche, Rebecca L Haffajee

Open access · goldAbstract read
In one paragraph

Article in Addiction science & clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Barbara Andraka-ChristouSchool of Global Health Management and Informatics, University of Central Florida, 500 W Livingston Ave, Suite 400, FL, Orlando, USA. barbara.andraka@ucf.edu.ORCID 0000-0001-6307-6369
Cory PageBehavioral and Physical Health and Aging Services Administration, Department of Health and Human Services, Lansing, MI, USA.
Victoria SchoebelSchool of Public Health, University of Minnesota, Minneapolis, MI, USA.ORCID 0000-0001-9211-6120
Jessica BucheDepartment of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-1726-047X
Rebecca L HaffajeeAssistant Secretary for Planning and Evaluation, U.S. Department of Health and Human Services, Washington D.C., USA.ORCID 0000-0003-0123-1516
University of Michigan · USSubstance Abuse and Mental Health Services Administration · USUniversity of Central Florida · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedications for opioid use disorder (MOUDs), including methadone, buprenorphine, and naltrexone, decrease mortality and morbidity for people with opioid use disorder (OUD). Buprenorphine and methadone have the strongest evidence base among MOUDs. Unlike methadone, buprenorphine may be prescribed in office-based settings in the U.S., including by nurse practitioners (NPs) and physician assistants (PAs) who have a federal waiver and adhere to federal patient limits. Buprenorphine is underutilized nationally, particularly in rural areas, and NPs/PAs could help address this gap. Therefore, we sought to identify perceptions of buprenorphine efficacy and perceptions of prescribing barriers among NPs/PAs. We also sought to compare perceived buprenorphine efficacy and perceived prescribing barriers between waivered and non-waivered NPs/PAs, as well as to compare perceived buprenorphine efficacy to perceived naltrexone and methadone efficacy.

methodsWe disseminated an online survey to a random national sample of NPs/PAs. We used Mann-Whitney U tests to compare between waivered and non-waivered respondents. We used non-parametric Friedman tests and post-hoc Wilcoxon signed-rank tests to compare perceptions of medication types.

results240 respondents participated (6.5% response rate). Most respondents agreed buprenorphine is efficacious and believed counseling and peer support should complement buprenorphine. Buprenorphine was generally perceived as more efficacious than both naltrexone and methadone. Perceived buprenorphine efficacy and prescribing barriers differed by waiver status. Non-waivered practitioners were more likely than waivered practitioners to have concerns about buprenorphine affecting patient mix. Among waivered NPs/PAs, key buprenorphine prescribing barriers were insurance prior authorization and detoxification access.

conclusionsOur results suggest that different policies should target perceived barriers affecting waivered versus non-waivered NPs/PAs. Concerns about patient mix suggest stigmatization of patients with OUD. NP/PA education is needed about comparative medication efficaciousness, particularly regarding methadone. Even though many buprenorphine treatment patients benefits from counseling and/or peer support groups, NPs/PAs should be informed that such psychosocial treatment methods are not necessary for all buprenorphine patients.

Indexed as

BuprenorphineNurse PractitionersOpioid-Related DisordersPhysician AssistantsHumansMethadoneNaltrexoneOpiate Substitution TreatmentBuprenorphineMethadoneNaltrexoneBarriersBuprenorphineCounselingDetoxificationEfficacyMethadoneNaltrexoneNurse practitionersPeer supportPerceptionsPhysician assistantsPrior authorizationSurvey

Identifiers

PMID35945636
PMCPMC9364483
OpenAlexW4291019828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.