ReviewParasites & vectors2022
Aedes aegypti and Ae. albopictus microbiome/virome: new strategies for controlling arboviral transmission?
Review in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Systematic review of Aedes aegypti control trials suggests publication bias related to author disclosure of conflicts of interest.PLoS neglected tropical diseases · 2026Pooled it
- Transcriptional responses of Aedes aegypti chemosensory tissues in response to volatile DEET and citronella oil.Insect molecular biology · 2026Article
- Bacterial and Fungal Microbiota in Anopheles darlingi Exhibit Differences in Diversity Across Three Main Colombian Malaria-endemic Regions.Microbial ecology · 2026Article
- Evaluation of Insecticide Resistance inInsects · 2026Article
- Microbiota variation inMicrobiology spectrum · 2026Article
- The Mitogenomes and Phylogenetic Relationships of the Tribe Aedini in Culicidae (Diptera).Ecology and evolution · 2026Article
- Climate and socioeconomic factors drive heterogeneous dengue risk escalation in the Chinese population.Communications medicine · 2026Article
- Spatiotemporal variation in the microbiome ofMicrobiology spectrum · 2026Article
- Differences in metaviromes between Aedes aegypti and Aedes albopictus from sympatric areas on Hainan Island and the Leizhou Peninsula, China.Parasites & vectors · 2026Article
- Metagenomic analysis of bacterial and viral communities of Aedes aegypti and Aedes albopictus.Journal, genetic engineering & biotechnology · 2026Article
- Differences in metavirome among Aedes albopictus, Culex tritaeniorhynchus, and Anopheles sinensis in Jiangxi Province, China.Parasites & vectors · 2026Article
- Horizons of the Future: Preparedness and Response.Current topics in microbiology and immunology · 2026Review
- Article
- Characterizing the Bacterial Microbiome of the Invasive VectorInternational journal of microbiology · 2026Article
- Article
- Oviposition response of Aedes mosquitoes to different cement types: a field-based study in urban Sri Lanka.BMC research notes · 2025Article
- Low genetic diversity of Aedes albopictus (Diptera: Culicidae) in El Salvador based on mitochondrial COI sequences: evidence of a well-preserved ancestral lineage in the Americas.Journal of insect science (Online) · 2025Article
- Global distribution and impact of knockdown resistance mutations in Aedes aegypti on pyrethroid resistance.Parasites & vectors · 2025Review
- Indicator bacteria taxa reveal breeding site origins of Aedes aegypti mosquitoes.BMC research notes · 2025Article
- Exceptional Heme Tolerance inLife (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aedes aegypti and Aedes albopictus are the main vectors of highly pathogenic viruses for humans, such as dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which cause febrile, hemorrhagic, and neurological diseases and remain a major threat to global public health. The high ecological plasticity, opportunistic feeding patterns, and versatility in the use of urban and natural breeding sites of these vectors have favored their dispersal and adaptation in tropical, subtropical, and even temperate zones. Due to the lack of available treatments and vaccines, mosquito population control is the most effective way to prevent arboviral diseases. Resident microorganisms play a crucial role in host fitness by preventing or enhancing its vectorial ability to transmit viral pathogens. High-throughput sequencing and metagenomic analyses have advanced our understanding of the composition and functionality of the microbiota of Aedes spp. Interestingly, shotgun metagenomics studies have established that mosquito vectors harbor a highly conserved virome composed of insect-specific viruses (ISV). Although ISVs are not infectious to vertebrates, they can alter different phases of the arboviral cycle, interfering with transmission to the human host. Therefore, this review focuses on the description of Ae. aegypti and Ae. albopictus as vectors susceptible to infection by viral pathogens, highlighting the role of the microbiota-virome in vectorial competence and its potential in control strategies for new emerging and re-emerging arboviruses.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.