Evidence map›Paper›PMID 35945308›Full record

ArticleNeurochemical research2022

The Pharmacological Effects of Phenylephrine are Indirect, Mediated by Noradrenaline Release from the Cytoplasm.

Mahmoud Al-Khrasani, David A Karadi, Anna R Galambos, Beata Sperlagh, E Sylvester Vizi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurochemical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Functional characterization of the αFrontiers in pharmacology · 2025
    Article
  4. Activation of IPAmerican journal of physiology. Heart and circulatory physiology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahmoud Al-KhrasaniDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4., Budapest, 1089, Hungary.
David A KaradiDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4., Budapest, 1089, Hungary.
Anna R GalambosDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4., Budapest, 1089, Hungary.
Beata SperlaghInstitute of Experimental Medicine, Eötvös Lóránd Research Network, Szigony utca 43., Budapest, 1083, Hungary.
E Sylvester ViziDepartment of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4., Budapest, 1089, Hungary. esvizi@koki.hu.ORCID http://orcid.org/0000-0002-9557-4597

Funding

Semmelweis Egyetem NRDI fund (TKP2021-EGA-25)
6 · The paper itself

Abstract

Phenylephrine (PE) is a canonical α

Indexed as

Adrenergic alpha-AntagonistsNorepinephrineAdrenergic alpha-AgonistsAnimalsCytoplasmMaleMicePhenylephrinePrazosinReceptors, Adrenergic, alpha-1Adrenergic alpha-AgonistsAdrenergic alpha-AntagonistsNorepinephrinePhenylephrinePrazosinReceptors, Adrenergic, alpha-1Cytoplasmic originIndirect actionNoradrenaline releaseNoradrenaline transporterPhenylephrineα1-Adrenoceptor

Identifiers

PMID35945308
PMCPMC9546997

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.