Evidence map›Paper›PMID 35945239›Full record

ArticleScientific reports2022

A lightweight magnetically shielded room with active shielding.

Niall Holmes, Molly Rea, James Chalmers, James Leggett, Lucy J Edwards, Paul Nell, Stephen Pink, Prashant Patel, Jack Wood, Nick Murby and 16 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 112 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. SPM-30 years and beyond.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Review
  6. Wearable Magnetoencephalography in a Lightly Shielded Environment.IEEE transactions on bio-medical engineering · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Determining sensor geometry and gain in a wearable MEG system.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 6 institutions in 3 countries.

Niall HolmesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. niall.holmes@nottingham.ac.uk.
Molly ReaSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
James ChalmersMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
James LeggettSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Lucy J EdwardsSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Paul NellMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Stephen PinkMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Prashant PatelMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Jack WoodMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Nick MurbyMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
David WoolgerMagnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Eliot DawsonCerca Magnetics Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Christopher MarianiCerca Magnetics Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.
Tim M TierneyWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.
Stephanie MellorWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.
George C O'NeillWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.
Elena BotoSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Ryan M HillSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Vishal ShahQuSpin Inc., 331 South 104th Street, Suite 130, Louisville, CO, 80027, USA.
James OsborneQuSpin Inc., 331 South 104th Street, Suite 130, Louisville, CO, 80027, USA.
Rosemarie PardingtonYoung Epilepsy, St. Piers Lane, Lingfield, Surrey, RH7 6PW, UK.
Peter FierlingerDepartment of Physics, Technical University Munich, 85748, Garching, Germany.
Gareth R BarnesWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.
Paul GloverSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Matthew J BrookesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Richard BowtellSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
University of Nottingham · GBWellcome Centre for Human Neuroimaging · GBPrinted Electronics (United Kingdom) · GBQuSpin (United States) · USEpilepsy Action · GBTechnical University of Munich · DE

Funding

High-resolution Non-cryogenic Magnetoencephalography: Systems-Level IntegrationR44MH110288 · NIMH · QUSPIN · PI SHAH, VISHAL K · 2016 to 2022
$5.1M
NIMH NIH HHS R44 MH110288Wellcome Trust 203257/B/16/ZWellcome Trust 203257/Z/16/Z
6 · The paper itself

Abstract

Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision magnetic field measurements such as magnetoencephalography (MEG). Optically pumped magnetometers (OPMs) have enabled the development of wearable MEG systems which have the potential to provide a motion tolerant functional brain imaging system with high spatiotemporal resolution. Despite significant promise, OPMs impose stringent magnetic shielding requirements, operating around a zero magnetic field resonance within a dynamic range of ± 5 nT. MSRs developed for OPM-MEG must therefore effectively shield external sources and provide a low remnant magnetic field inside the enclosure. Existing MSRs optimised for OPM-MEG are expensive, heavy, and difficult to site. Electromagnetic coils are used to further cancel the remnant field inside the MSR enabling participant movements during OPM-MEG, but present coil systems are challenging to engineer and occupy space in the MSR limiting participant movements and negatively impacting patient experience. Here we present a lightweight MSR design (30% reduction in weight and 40-60% reduction in external dimensions compared to a standard OPM-optimised MSR) which takes significant steps towards addressing these barriers. We also designed a 'window coil' active shielding system, featuring a series of simple rectangular coils placed directly onto the walls of the MSR. By mapping the remnant magnetic field inside the MSR, and the magnetic field produced by the coils, we can identify optimal coil currents and cancel the remnant magnetic field over the central cubic metre to just |B|= 670 ± 160 pT. These advances reduce the cost, installation time and siting restrictions of MSRs which will be essential for the widespread deployment of OPM-MEG.

Indexed as

Functional NeuroimagingMagnetoencephalographyBrainHumansMagnetic FieldsMagnetic Resonance ImagingMagnetic Resonance Spectroscopy

Identifiers

PMID35945239
PMCPMC9363499
OpenAlexW4291020559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.