Evidence map›Paper›PMID 35945030›Full record

ReviewInternal medicine (Tokyo, Japan)2023

Possible Chronic Graft-versus-host Disease in the Central Nervous System Manifesting as Cerebellar Ataxia after Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia.

Kae Takahashi, Takayuki Katayama, Takaya Ichikawa, Satomi Matsuoka, Yasutaka Kakinoki, Makoto Yoneda, Akio Kimura, Satoshi Koyama, Osamu Yahara

Open access · diamondAbstract readReviewCase Reports
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kae TakahashiDepartment of Neurology, Asahikawa City Hospital, Japan.
Takayuki KatayamaDepartment of Neurology, Asahikawa City Hospital, Japan.
Takaya IchikawaDepartment of Hematology, Asahikawa City Hospital, Japan.
Satomi MatsuokaDepartment of Hematology, Asahikawa City Hospital, Japan.
Yasutaka KakinokiDepartment of Hematology, Asahikawa City Hospital, Japan.
Makoto YonedaFaculty of Nursing and Social Welfare Science, Fukui Prefectural University, Japan.
Akio KimuraDepartment of Neurology, Gifu University, Japan.
Satoshi KoyamaDepartment of Internal Medicine, Asahikawa Rehabilitation Hospital, Japan.
Osamu YaharaDepartment of Neurology, Asahikawa City Hospital, Japan.
Asahikawa City Hospital · JPFukui Prefectural University · JPGifu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 44-year-old woman was admitted to our hospital with a fever, dizziness, and gait disturbance after undergoing allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia followed by graft-versus-host disease. She presented with cerebellar ataxia, nystagmus, and numbness of the lower extremities. Brain magnetic resonance imaging and perfusion scintigraphy showed progressive cerebellar involvement. Cerebrospinal fluid tests showed mildly elevated protein and IgG levels without pleocytosis. Anti-ganglioside antibodies were detected, but their levels did not follow the patient's clinical course. The patient did not respond sufficiently to steroids or other immunotherapies. We herein report the clinical characteristics of this case and a literature review.

Indexed as

Bronchiolitis Obliterans SyndromeCerebellar AtaxiaGraft vs Host DiseaseHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAdultCentral Nervous SystemFemaleHumansTransplantation, Homologousallogeneic hematopoietic stem cell transplantationataxiacentral nervous systemdownbeat nystagmusgraft-versus-host diseaseleukemia

Identifiers

PMID35945030
PMCPMC10037021
OpenAlexW4291633022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.