Evidence map›Paper›PMID 35945009›Full record

ReviewInternal medicine (Tokyo, Japan)2022

A Novel Development of Sarcoidosis Following COVID-19 Vaccination and a Literature Review.

Tadahisa Numakura, Koji Murakami, Tsutomu Tamada, Chiaki Yamaguchi, Chihiro Inoue, Shinya Ohkouchi, Naoki Tode, Hirohito Sano, Hiroyuki Aizawa, Kei Sato and 4 more

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Prevalence of SARS-COV-2 infection and outcomes in Greek sarcoidosis patients.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Vogt-Koyanagi-Harada Disease and COVID.Journal of clinical medicine · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Tadahisa NumakuraDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Koji MurakamiDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Tsutomu TamadaDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Chiaki YamaguchiDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Japan.
Chihiro InoueDepartment of Anatomic Pathology, Tohoku University Graduate School of Medicine, Japan.
Shinya OhkouchiDepartment of Occupational Health, Tohoku University Graduate School of Medicine, Japan.
Naoki TodeDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Hirohito SanoDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Hiroyuki AizawaDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Kei SatoDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Ayumi MitsuneDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Hajime KurosawaDepartment of Occupational Health, Tohoku University Graduate School of Medicine, Japan.
Toru NakazawaDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Japan.
Hisatoshi SugiuraDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BNT162b2 (Pfizer/BioNTech) is a coronavirus disease 2019 (COVID-19) vaccine containing nucleoside-modified messenger RNA encoding the severe acute respiratory syndrome coronavirus 2 spike glycoprotein. Recently, ocular complications of mRNA vaccines have been reported increasingly frequently. However, immunological adverse events due to mRNA vaccines in real-world settings are not fully known. We herein report the novel development of sarcoidosis manifested as uveitis, bilateral hilar lymphadenopathy, angiotensin-converting enzyme elevation, and epithelioid and giant cell granuloma formation in the lung soon after the first BNT162b2 injection and review the current literature, including three reported cases of sarcoid-like reaction following COVID-19 vaccination.

Indexed as

COVID-19COVID-19 VaccinesSarcoidosisAngiotensinsBNT162 VaccineHumansSpike Glycoprotein, CoronavirusVaccinationAngiotensinsBNT162 VaccineCOVID-19 VaccinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2angiotensin-converting enzyme (ACE)COVID-19mRNA vaccinesarcoidosisuveitis

Identifiers

PMID35945009
PMCPMC9646347
OpenAlexW4291632948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.