Evidence map›Paper›PMID 35944943›Full record

ArticleBMJ open respiratory research2022

Differences in severe exacerbations rates and healthcare utilisation in COPD populations in the UK and France.

Hannah Whittaker, Eric Van Ganse, Faustine Dalon, Maeva Nolin, Claire Marrant-Micallef, Christophe Pison, Dermot P Ryan, Gaetan Deslee, Jennifer K Quint, Manon Belhassen

Open access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. How People with COPD Perceive and Communicate Exacerbations: A Multicountry Survey Study.International journal of chronic obstructive pulmonary disease · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Hannah WhittakerNational Heart and Lung Institute, Imperial College London, London, UK h.whittaker@imperial.ac.uk.
Eric Van GansePELyon, Pharmaco Epidemiologie Lyon, Lyon, France.
Faustine DalonPELyon, Pharmaco Epidemiologie Lyon, Lyon, France.
Maeva NolinPELyon, Pharmaco Epidemiologie Lyon, Lyon, France.
Claire Marrant-MicallefPELyon, Pharmaco Epidemiologie Lyon, Lyon, France.
Christophe PisonClinique de Pneumologie, Centre Hospitalier Universitaire de Grenoble, Service de Pneumologie, Grenoble, France.
Dermot P RyanAllergy and Respiratory Research Group, Centre for Population Health Sciences: GP Section, University of Edinburgh, Edinburgh, UK.
Gaetan DesleeDepartment of Respiratory Medicine, INSERM UMRS 903, University Hospital of Reims, Reims, France.
Jennifer K Quint *National Heart and Lung Institute, Imperial College London, London, UK.
Manon Belhassen *PELyon, Pharmaco Epidemiologie Lyon, Lyon, France.
Imperial College London · GBFractionnation of AgroResources and Environment · FRHôpital de la Croix-Rousse · FRUniversité Grenoble Alpes · FRUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic obstructive pulmonary disease (COPD) is a leading cause of mortality in Europe; however, it is important to understand how clinical practice patterns differ between countries and how this might relate to disease outcomes, to identify ways of improving local disease management. We aimed to describe and compare the management of patients with COPD in the UK and France between 2008 and 2017.

methodsWe used data from the Clinical Practice Research Datalink GOLD and Hospital Episode Statistics in the UK and the Echantillon Généraliste des Bénéficiaire in France to identify patients with COPD each year between 2008 and 2017. We compared patient characteristics, all-cause mortality and COPD exacerbations each year between 2008 and 2017 for patients in the UK and France separately. Health care utilisation and COPD exacerbations in 2017 were compared between France and the UK using t-tests and χ

resultsPatients with COPD were similar in gender and comorbidities in both countries. Incidence of COPD exacerbations remained stable in the UK and France between 2007 and 2017. In 2017, the proportion of all-cause and COPD-related hospitalisations was greater in the UK than in France (43.9% vs 32.8% and 8.3% vs 4.9%, respectively; p<0.001) as was the proportion of patients visiting accident and emergency (A&E) (39.8% vs 16.2%, respectively; p<0.001). In addition, the mean length of stay in hospital for COPD-related causes was shorter in the UK than in France (6.2 days (SD 8.4) vs 10.5 days (SD 9.1), respectively; p<0.001). DISCUSSION: Overall, UK patients were more likely to go to A&E, be hospitalised for COPD-related causes and stay in hospital for fewer days after being admitted for COPD-related reasons compared with patients in France, illustrating a difference in health-seeking behaviours and access to healthcare.

Indexed as

Pulmonary Disease, Chronic ObstructiveDisease ProgressionFranceHumansPatient Acceptance of Health CareUnited KingdomCOPD epidemiology

Identifiers

PMID35944943
PMCPMC9367183
OpenAlexW4290792265

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.