Trial reportAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2023
Effect of Long-term Exercise Training on Physical Performance and Cardiorespiratory Function in Adults With CKD: A Randomized Controlled Trial.
Trial report in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Trial of Aerobic Exercise Training on Cognitive and Physical Function in Chronic Kidney Disease
Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients: A Single Center Prospective Randomized Controlled Study
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Benefits of physical exercises in chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials.Renal failure · 2026Pooled it
- Effects of exercise training on frailty, cardiorespiratory fitness, and lower limb function in non-dialysis chronic kidney disease: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Pooled it
- The effect of exercise training in people with pre-dialysis chronic kidney disease: a systematic review with meta-analysis.Journal of nephrology · 2024Pooled it
- Effects of whole-body vibration exercise on physical function in patients with chronic kidney disease: a systematic review and meta-analysis.BMC nephrology · 2024Pooled it
- The Borg scale is safe and efficacious for prescribing and monitoring self-administered balance and resistance exercise in patients with chronic kidney disease: a post-hoc analysis of RENEXC, a randomized controlled trial.Journal of rehabilitation medicine · 2025Trial
- Effects of different exercises on renal and cardiovascular function in adult patients with chronic kidney disease not receiving dialysis: a network meta-analysis.BMC nephrology · 2026Article
- Determining Physical Function Measures for Estimating VOKidney medicine · 2026Article
- 67 national-level factors potentially related to the incidence of kidney replacement therapy across Europe.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Article
- An Integrated, Evidence-Guided Framework for Chronic Kidney Disease Self-Management: Behavioral Mechanisms, Implementation Strategies, and Real-World Application.Kidney & blood pressure research · 2026Review
- Association of Physical Activity with Abdominal Aortic Calcification in Chronic Kidney Disease: A Cross-Sectional Study.Kidney & blood pressure research · 2026Article
- Physical activity in kidney disease: evidence and implementation.Nature reviews. Nephrology · 2025Review
- [Effect of Blood Biochemical Indicators on Exercise Duration in Patients With Stages 3-5 Chronic Kidney Disease: The Mediating Role of Physical Function Status].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Physical activity and cardiorenal health-from associations to interventional studies.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Patient Activation Impacts Exercise in Older Adults With Kidney Disease.Kidney international reports · 2025Article
- Proton-Sensing G Protein-Coupled Receptors and Their Potential Role in Exercise Regulation of Arterial Function.Biomolecules · 2025Review
- Functional Performance Decline Outperforms Sarcopenia and Its Components in Predicting New-Onset Chronic Kidney Disease: A Nationwide Multicenter Study.Kidney medicine · 2025Article
- Precision management in chronic disease: An AI empowered perspective on medicine-engineering crossover.iScience · 2025Review
- Screening and prognostic roles of renal volumetry and scintigraphy in the assessment of living kidney transplant donors, considering the early recovery of the residual renal function.BMC nephrology · 2025Article
- Handgrip weakness and overall life satisfaction decline: derivation of cutoff values and analysis of sex differences in older Chinese adults.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
RATIONALE &
objectiveThe safety and efficacy of long-term exercise training in reducing physical functional loss in older adults with advanced CKD and comorbidity is uncertain. STUDY
designMulticenter, parallel group, randomized controlled trial. SETTINGS &
participantsAdults 55 years and older with estimated glomerular filtration rate (eGFR) of 15 to <45 mL/min/1.73 m
interventionTwelve months of in-center supervised exercise training incorporating majority aerobic but also muscle strengthening activities or a group health education control intervention, randomly assigned in 1:1 ratio. OUTCOME: Primary outcomes were cardiorespiratory fitness and submaximal gait at 6 and 12 months quantified by peak oxygen consumption (Vo
resultsAmong 99 participants, the mean age was 68 years, 62% were African American, and the mean eGFR was 33 mL/min/1.73 m LIMITATIONS: Planned sample size was not reached. Loss to follow-up and dropout were greater than anticipated.
conclusionsAmong adults aged ≥55 years with CKD stages 3b-4 and a high level of medical comorbidity, a 12-month program of in-center aerobic and resistance exercise training was safe and associated with improvements in physical functioning.
fundingGovernment grants (National Institutes of Health).
trial registrationRegistered at ClinicalTrials.gov with study number NCT01462097.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.