Evidence map›Paper›PMID 35944728›Full record

ArticleThe American journal of pathology2022

Resolvin E1 Reduces Tumor Growth in a Xenograft Model of Lung Cancer.

Alpdogan Kantarci, Shevali Kansal, Hatice Hasturk, Danielle Stephens, Thomas E Van Dyke

Open access · greenAbstract read
In one paragraph

Article in The American journal of pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Long-chain Polyunsaturated Fatty Acids MitigatebioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alpdogan KantarciForsyth Institute, Cambridge, Massachusetts. Electronic address: akantarci@forsyth.org.
Shevali KansalForsyth Institute, Cambridge, Massachusetts.
Hatice HasturkForsyth Institute, Cambridge, Massachusetts.
Danielle StephensForsyth Institute, Cambridge, Massachusetts.
Thomas E Van DykeForsyth Institute, Cambridge, Massachusetts.
Forsyth Technical Community College · US

Funding

Mechanisms of Resolvin E1 in Periodontal RegenerationR01DE025020 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI VAN DYKE, THOMAS ELLIOTT · 2015 to 2023
$4.9M
Treatment of Periodontitis and Inflammatory Changes in DiabetesK23DE018917 · NIDCR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HASTURK, HATICE · 2008 to 2012
$647k
Hypoxia and PMN Function in PeriodontitisR21DE020906 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI KANTARCI, IBRAHIM ALPDOGAN · 2011 to 2012
$478k
NIDCR NIH HHS K23 DE018917NIDCR NIH HHS R01 DE025020NIDCR NIH HHS R21 DE020906
6 · The paper itself

Abstract

Inflammation plays a significant role in carcinogenesis and tumor growth. The current study was designed to test the hypothesis that resolvin E1 (RvE1) and overexpression of the receptor for RvE1 (ERV1) will prevent and/or reverse tumor generation in a gain-of-function mouse model of tumor seeding with lung cancer cells. To measure the impact of enhanced resolution of inflammation on cancer pathogenesis, ERV1-overexpressing transgenic (TG) and wild-type FVB mice were given an injection of 1 × 10

Indexed as

Lung NeoplasmsVascular Endothelial Growth Factor AAngiopoietinsAnimalsCisplatinCyclooxygenase 2CytokinesDisease Models, AnimalEicosapentaenoic AcidHeterograftsInflammationKi-67 AntigenMiceNF-kappa B5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acidAngiopoietinsCisplatinCyclooxygenase 2CytokinesEicosapentaenoic AcidKi-67 AntigenNF-kappa BVascular Endothelial Growth Factor A

Identifiers

PMID35944728
PMCPMC9552033
OpenAlexW4290058929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.