ArticleEuropean journal of dentistry2023
The Effects of Radiotherapy on Microhardness and Mineral Composition of Tooth Structures.
Article in European journal of dentistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- The Effect of Radiotherapy on the Microtensile Bond Strength of Dentin in Relation to the Timing of Restoration Procedure.International journal of dentistry · 2026Article
- Dual therapy with nanohydroxyapatite and vitamin E restores irradiated dentin via remineralization and collagen protection.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Evaluating microbial regulation as a preventive strategy for radiation-related caries: A review.Head & face medicine · 2025Review
- Effect of different protocols in preventing demineralization in irradiated human enamel, in vitro study.BMC oral health · 2025Article
- Effects of radiation therapy on the morphology and composition of root dentin and cementum in primary teeth.Brazilian oral research · 2025Article
- Review
- Effect of different approaches of direct radiation on the surface structure and caries susceptibility of enamel.Scientific reports · 2024Article
- Preventive and restorative alternatives to caries by irradiation: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to evaluate the microhardness and mineral composition alterations in enamel and dentine after radiotherapy. MATERIALS AND
methodsForty human maxillary premolar teeth (20 pairs) were assigned to nonirradiated and irradiated groups, the latter irradiated by fractional radiation to achieve a total dose of 70 Gy. Microhardness measurement was performed on a Knoop microhardness tester. Chemical components were analyzed using energy dispersive spectroscopy and Fourier transform Raman spectroscopy. The morphology was observed using a scanning electron microscope. The microhardness data were analyzed using a paired
resultsThe irradiated teeth had a significantly lower microhardness in both enamel and dentine compared with the nonirradiated teeth. The irradiated dentine at 50 μm from the external tooth surface at the cemento-enamel junction showed the lowest microhardness compared with other locations. There was no statistically significant difference in calcium:phosphate ratio and chemical components. There was a reduction in protein:mineral ratio in dentine and at the cemento-enamel junction after irradiation. The irradiated teeth exhibited crack lines at the dentine-enamel junction and in dentine.
conclusionFractional radiation reduced microhardness in both enamel and dentine. The cervical dentine exhibited the highest microhardness reduction compared with other enamel and dentine locations.
Identifiers
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Registered trials
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