ArticleThe journal of physical chemistry. B2022
Blocker Effect on Diffusion Resistance of a Membrane Channel: Dependence on the Blocker Geometry.
Article in The journal of physical chemistry. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Modeling Diffusion of Elongated Particles Through a Narrowing Channel.Entropy (Basel, Switzerland) · 2025Article
- Diffusion Resistance of Segmented Channels.The journal of physical chemistry. B · 2023Article
- Permeability and diffusion resistance of porous membranes: Analytical theory and its numerical test.The Journal of chemical physics · 2023Article
- Blockage coefficient of cylindrical blocker and diffusion resistance of membrane channels.Physics of fluids (Woodbury, N.Y. : 1994) · 2023Article
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Authors and funding
4 authors.
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Abstract
Being motivated by recent progress in nanopore sensing, we develop a theory of the effect of large analytes, or blockers, trapped within the nanopore confines, on diffusion flow of small solutes. The focus is on the nanopore diffusion resistance which is the ratio of the solute concentration difference in the reservoirs connected by the nanopore to the solute flux driven by this difference. Analytical expressions for the diffusion resistance are derived for a cylindrically symmetric blocker whose axis coincides with the axis of a cylindrical nanopore in two limiting cases where the blocker radius changes either smoothly or abruptly. Comparison of our theoretical predictions with the results obtained from Brownian dynamics simulations shows good agreement between the two.
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