Evidence map›Paper›PMID 35943985›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Distinct neural networks derived from galanin-containing nociceptors and neurotensin-expressing pruriceptors.

Yan Chen, Yuran Song, Huadong Wang, Yiyun Zhang, Xinyu Hu, Kaikai Wang, Yingjin Lu, Zoutao Zhang, Shuai Li, Anan Li and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Central neural circuits underlying itch sensation.Nature reviews. Neuroscience · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Virus-Based Neural Circuit Tracing.Advances in neurobiology · 2024
    Review
  10. Article
  11. Distinct neural networks derived from galanin-containing nociceptors and neurotensin-expressing pruriceptors.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Yan ChenGuangdong Institute of Intelligence Science and Technology, 519031 Zhuhai, China.
Yuran SongInstitute of Neuroscience and State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, University of Chinese Academy of Sciences, CAS; Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai, 200031 China.ORCID 0000-0003-1218-4719
Huadong WangNMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products, Shenzhen Key Laboratory of Viral Vectors for Biomedicine, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055 China.ORCID 0000-0003-2388-6062
Yiyun ZhangResearch Unit of Pain Medicine, Chinese Academy of Medical Sciences; SIMR Joint Lab of Drug Innovation, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210 China.
Xinyu HuResearch Unit of Pain Medicine, Chinese Academy of Medical Sciences; SIMR Joint Lab of Drug Innovation, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210 China.
Kaikai WangResearch Unit of Pain Medicine, Chinese Academy of Medical Sciences; SIMR Joint Lab of Drug Innovation, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210 China.
Yingjin LuGuangdong Institute of Intelligence Science and Technology, 519031 Zhuhai, China.
Zoutao ZhangHuazhong University of Science and Technology-Suzhou Institute for Brainsmatics, Jiangsu Industrial Technology Research Institute for Brainsmatics, 215000 Suzhou, China.
Shuai LiGuangdong Institute of Intelligence Science and Technology, 519031 Zhuhai, China.ORCID 0000-0002-6892-5224
Anan LiHuazhong University of Science and Technology-Suzhou Institute for Brainsmatics, Jiangsu Industrial Technology Research Institute for Brainsmatics, 215000 Suzhou, China.
Lan BaoGuangdong Institute of Intelligence Science and Technology, 519031 Zhuhai, China.
Fuqiang XuNMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products, Shenzhen Key Laboratory of Viral Vectors for Biomedicine, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055 China.
Changlin LiGuangdong Institute of Intelligence Science and Technology, 519031 Zhuhai, China.
Xu ZhangGuangdong Institute of Intelligence Science and Technology, 519031 Zhuhai, China.
Chinese Academy of Sciences · CNHKUST Shenzhen Research Institute · CNSuzhou Research Institute · CNGuangdong Polytechnic of Science and Technology · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain and itch are distinct sensations arousing evasion and compulsive desire for scratching, respectively. It's unclear whether they could invoke different neural networks in the brain. Here, we use the type 1 herpes simplex virus H129 strain to trace the neural networks derived from two types of dorsal root ganglia (DRG) neurons: one kind of polymodal nociceptors containing galanin (

Indexed as

GalaninGanglia, SpinalNerve NetNeurotensinNociceptorsPainPruritusAnimalsHerpesvirus 1, HumanMiceMice, TransgenicSolitary NucleusGalaninNeurotensindorsal root gangliaherpes simplex virusitchneural networkpain

Identifiers

PMID35943985
PMCPMC9388111
OpenAlexW4291019707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.