ArticleLa Radiologia medica2022
Contrast-enhanced ultrasound in the assessment of Crohn's disease activity: comparison with computed tomography enterography.
Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Diagnostic Accuracy of Intestinal Ultrasound in the Detection of Intra-Abdominal Complications in Crohn's Disease: A Systematic Review and Meta-Analysis.Journal of Crohn's & colitis · 2024Pooled it
- A novel super-resolution contrast-enhanced ultrasound approach for evaluating inflammatory activity in Crohn's disease.Insights into imaging · 2026Article
- The role of lipid metabolism and creeping fat in disease assessment and prediction for Crohn's disease.Frontiers in immunology · 2026Review
- Diagnostic performance of intestinal ultrasound compared with CT enterography in Crohn's disease: single-center experience.Frontiers in medicine · 2025Article
- Network modeling of the impact of social support and illness acceptance on disease activity in Crohn's disease patients: a cross-sectional study.Frontiers in psychology · 2025Article
- Novelties and Perspectives of Intestinal Ultrasound in the Personalised Management of Patients with Inflammatory Bowel Diseases-A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Application of Dynamic Contrast-Enhanced Ultrasound in Evaluation the Activity of Crohn's Disease.Diagnostics (Basel, Switzerland) · 2024Article
- Deep-Learning, Radiomics and Clinic Based Fusion Models for Predicting Response to Infliximab in Crohn's Disease Patients: A Multicentre, Retrospective Study.Journal of inflammation research · 2024Article
- Peritoneal Carcinosis: What the Radiologist Needs to Know.Diagnostics (Basel, Switzerland) · 2023Review
- Recent Advances in Ultrasound Breast Imaging: From Industry to Clinical Practice.Diagnostics (Basel, Switzerland) · 2023Review
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectiveContinuous assessment of disease activity remains a huge challenge during the follow-ups of patients with Crohn's disease (CD). In this paper, we aimed to evaluate the performance of contrast-enhanced ultrasound (CEUS) by comparing with computed tomography enterography (CTE) in the assessment of disease activity in CD. MATERIALS AND
methodsFifty-two patients diagnosed with CD were included in this study, using the CEUS and CTE as imaging methods for comparison. The selected parameters included the location and thickness of the thickest part of the intestinal wall, mesenteric fat proliferation, mesenteric vessels change, enhancement pattern and the presence of complications. Patients were clinically assessed using the Crohn's disease activity index (CDAI), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Simple endoscopic score for Crohn's disease (SES-CD) was regarded as the reference standard.
resultsThe location of the thickest part of the intestinal wall (κ = 0.653), bowel wall thickness (ICC = 0.795), mesenteric vessels change (κ = 0.692) and complications (κ = 0.796) displayed substantial agreement (0.61-0.80) between CEUS and CTE, while the detection of mesenteric fat proliferation (κ = 0.395) and enhancement pattern (κ = 0.288) showed fair consistency (0.21-0.40) for comparison. In CEUS, bowel wall thickness, mesenteric fat proliferation, enhancement pattern and mesenteric vessels change were statistically significant in assessing CD activity, while bowel wall thickness, mesenteric fat proliferation and mesenteric vessels change in CTE. Bowel wall thickness showed the best diagnostic performance in the assessment of CD activity at CEUS and CTE.
conclusionCEUS provides a radiation-free and effective way to assess the CD activity in comparison with CTE, which also avoids frequent colonoscopy examinations, improves tolerance of patients, and reduces the cost of medical care, thereby serving as a useful tool for CD follow-up.
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