Evidence map›Paper›PMID 35943315›Full record

ArticleAnatolian journal of cardiology2022

Left Atrial Dysfunction as Marker of Arrhythmic Events in Patients with Hypertrophic Cardiomyopathy.

Özkan Candan, Çetin Geçmen, Muzaffer Kahyaoğlu, Mehmet Çelik, Zeki Şimşek, Ferhat Dindaş, Mustafa Doğduş, Regayip Zehir, Cevat Kırma

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In one paragraph

Article in Anatolian journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Özkan CandanDepartment of Cardiology, Faculty of Medicine, Uşak University, Uşak, Turkey.
Çetin GeçmenDepartment of Cardiology, Kartal Koşuyolu Training and Research Hospital, İstanbul, Turkey.
Muzaffer KahyaoğluDepartment of Cardiology, Kartal Koşuyolu Training and Research Hospital, İstanbul, Turkey.
Mehmet ÇelikDepartment of Cardiology, Kartal Koşuyolu Training and Research Hospital, İstanbul, Turkey.
Zeki ŞimşekDepartment of Cardiology, Kartal Koşuyolu Training and Research Hospital, İstanbul, Turkey.
Ferhat DindaşDepartment of Cardiology, Faculty of Medicine, Uşak University, Uşak, Turkey.
Mustafa DoğduşDepartment of Cardiology, Faculty of Medicine, Uşak University, Uşak, Turkey.
Regayip ZehirDepartment of Cardiology, Kartal Koşuyolu Training and Research Hospital, İstanbul, Turkey.
Cevat KırmaDepartment of Cardiology, Kartal Koşuyolu Training and Research Hospital, İstanbul, Turkey.
Kartal Koşuyolu High Specialization Training and Research Hospital · TRUsak University · TREskişehir City Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study, we investigated whether left atrial functions evaluated by speckle tracking echocardiography , classic echocardiographic and clinic parameters predict appropriate Implantable Cardioverter Defibrillator (ICD) shock in patients who underwent ICD implantation for hypertrophic cardiomyopathy.

methodsTotally 87 patients who received ICD implantation for primary or secondary prevention were included in the study. Patients' clinical, electrocardiographic, 2 dimen- sion classic, and speckle tracking echocardiographic data were collected. Left atrial functions were assessed by speckle tracking echocardiography. Left atrial strain just before mitral valve opening was taken as peak atrial longitudinal strain. Appropriate ICD therapy was defined as cardioversion or defibrillation due to ventricular tachycardia or fibrillation. Patients were divided into 2 groups as occurrence or absence of appropri- ate ICD therapy during follow-up (mean, 50.2 ± 9.3 months). Patients with an European Society of Cardiology (ESC) risk score >6% were considered high-risk patients.

resultsA total of 24 (27.5 %) patients were observed to have an appropriate ICD therapy. In patients on whom appropriate ICD therapy was performed, a higher Sudden Cardiac Death risk Score and decreased peak atrial longitudinal strain and global longitudinal peak strain were observed. In patients with high ESC risk score (> 6%), in Cox regres- sion analysis, peak atrial longitudinal strain (odds ratio: 0.806, P = .008), Sudden Cardiac Death risk score (odds ratio: 1.114, P = .03) and global longitudinal peak strain (odds ratio: 1.263, P = .02) were found to be independent predictors of occurrence of appropriate ICD therapy.

conclusionEasily measurable peak atrial longitudinal strain may provide additional information in predicting ventricular arrhythmias or deciding on prophylactic medical treatment to prevent ventricular arrhythmias or reduce the frequency of appropriate shock in high-risk patients with ICD implanted.

Indexed as

Cardiomyopathy, HypertrophicDefibrillators, ImplantableTachycardia, VentricularArrhythmias, CardiacDeath, Sudden, CardiacEchocardiographyHumansRisk Factors

Identifiers

PMID35943315
PMCPMC9623202
OpenAlexW4283796457

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.