Evidence map›Paper›PMID 35943157›Full record

ArticleFaraday discussions2022

The impact of AlphaFold2 on experimental structure solution.

Maximilian Edich, David C Briggs, Oliver Kippes, Yunyun Gao, Andrea Thorn

Abstract read
In one paragraph

Article in Faraday discussions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Generating Protein Structures for Pathway Discovery Using Deep Learning.Journal of chemical theory and computation · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Using AlphaFold Predictions in Viral Research.Current issues in molecular biology · 2023
    Review
  12. AlphaFold2 and its applications in the fields of biology and medicine.Signal transduction and targeted therapy · 2023
    Review
  13. Article
  14. Article
  15. The Active Site of the Enzyme 10-Formyl-THFDH in the Honey BeeInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maximilian EdichInstitute for Nanostructure and Solid State Physics, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany. andrea.thorn@uni-hamburg.de.ORCID http://orcid.org/0000-0002-0371-4784
David C BriggsThe Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.ORCID http://orcid.org/0000-0002-9793-7339
Oliver KippesInstitute for Nanostructure and Solid State Physics, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany. andrea.thorn@uni-hamburg.de.ORCID http://orcid.org/0000-0002-6231-8175
Yunyun GaoInstitute for Nanostructure and Solid State Physics, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany. andrea.thorn@uni-hamburg.de.ORCID http://orcid.org/0000-0001-7220-2638
Andrea ThornInstitute for Nanostructure and Solid State Physics, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany. andrea.thorn@uni-hamburg.de.ORCID http://orcid.org/0000-0003-4503-4258

Funding

Cancer Research UK CC2068Medical Research Council CC2068Wellcome Trust CC2068
6 · The paper itself

Abstract

AlphaFold2 is a machine-learning based program that predicts a protein structure based on the amino acid sequence. In this article, we report on the current usages of this new tool and give examples from our work in the Coronavirus Structural Task Force. With its unprecedented accuracy, it can be utilized for the design of expression constructs,

Indexed as

Computational BiologyProteinsAmino Acid SequenceMachine LearningModels, MolecularProtein ConformationProteins

Identifiers

PMID35943157
PMCPMC10231047

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.