Evidence map›Paper›PMID 35942478›Full record

ArticleFrontiers in psychiatry2022

Differential trajectories of tobacco smoking in people at ultra-high risk for psychosis: Associations with clinical outcomes.

Frederike Schirmbeck, Els van der Ven, Lindy-Lou Boyette, Philip McGuire, Lucia R Valmaggia, Matthew J Kempton, Mark van der Gaag, Anita Riecher-Rössler, Neus Barrantes-Vidal, Barnaby Nelson and 8 more

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In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 9 countries.

Frederike SchirmbeckDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Els van der VenDepartment of Clinical, Neuro- and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Lindy-Lou BoyetteDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, Netherlands.
Philip McGuireDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Lucia R ValmaggiaDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Matthew J KemptonDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Mark van der GaagDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Mental Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Anita Riecher-RösslerMedical Faculty, University of Basel, Basel, Switzerland.
Neus Barrantes-VidalDepartament de Psicologia Clínica i de la Salut, Universitat Autònoma de Barcelona, Barcelona, Spain.
Barnaby NelsonOrygen, Parkville, VIC, Australia.
Marie-Odile KrebsUniversity of Paris, GHU-Paris, Sainte-Anne, C'JAAD, Inserm U1266, Institut de Psychiatrie (CNRS 3557), Paris, France.
Stephan RuhrmannDepartment of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.
Gabriele SachsDepartment of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Bart P F RuttenDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, Netherlands.
Merete NordentoftMental Health Center Copenhagen, Department of Clinical Medicine, Copenhagen University Hospital, Copenhagen, Denmark.
EU-GEI High Risk Study Group
Lieuwe de HaanDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Jentien M VermeulenDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Amsterdam University Medical Centers · NLKing's College London · GBVrije Universiteit Amsterdam · NLCentre National de la Recherche Scientifique · FRCopenhagen University Hospital · DKMaastricht University Medical Centre · NLMedical University of Vienna · ATThe University of Melbourne · AUUniversitat Autònoma de Barcelona · ESUniversity of Amsterdam · NLUniversity of Basel · CHUniversity of Cologne · DE

Funding

Medical Research Council MR/J008915/1
6 · The paper itself

Abstract

Objective: People at ultra-high risk (UHR) for psychosis have a high prevalence of tobacco smoking, and rates are even higher among the subgroup that later develop a psychotic disorder. However, the longitudinal relationship between the course of tobacco smoking and clinical outcomes in UHR subjects is unknown. Methods: We investigated associations between tobacco smoking and clinical outcomes in a prospective study of UHR individuals ( Results: We identified four different classes of smoking trajectory: (i) Persistently High ( Conclusions: These findings suggests that in UHR subjects persistent tobacco smoking is associated with an unfavorable course of psychotic symptoms, whereas decrease in the number of cigarettes smoked is associated with improvement in affective symptoms. Future research into smoking cessation interventions in the early stages of psychoses is required to shine light on the potential of modifying smoking behavior and its relation to clinical outcomes.

Indexed as

affective symptomspsychosissmokingtobaccotrajectoriesultra-high risk

Identifiers

PMID35942478
PMCPMC9356251
OpenAlexW4297723922

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.