Evidence map›Paper›PMID 35942205›Full record

ReviewJournal of heterocyclic chemistry2022

Overview of Hydroxychloroquine and Remdesivir on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Arup K Kabi, Maynak Pal, Raghuram Gujjarappa, Chandi C Malakar, Mithun Roy

Open access · greenAbstract readReview
In one paragraph

Review in Journal of heterocyclic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. IntegratedCurrent medicinal chemistry · 2025
    Article
  4. Review
  5. Clinicopathological andCurrent medicinal chemistry · 2025
    Article
  6. COVID-19-Where Are We Now.Current medicinal chemistry · 2025
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Arup K KabiDepartment of Chemistry National Institute of Technology Manipur Imphal Manipur India.
Maynak PalDepartment of Chemistry National Institute of Technology Manipur Imphal Manipur India.
Raghuram GujjarappaDepartment of Chemistry National Institute of Technology Manipur Imphal Manipur India.ORCID https://orcid.org/0000-0002-2586-3190
Chandi C MalakarDepartment of Chemistry National Institute of Technology Manipur Imphal Manipur India.ORCID https://orcid.org/0000-0002-9478-017X
Mithun RoyDepartment of Chemistry National Institute of Technology Manipur Imphal Manipur India.
National Institute of Technology Manipur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the ongoing pandemic named COVID-19 which causes a serious emergency on public health hazards of international concern. In the face of a critical medical emergency, repositioning of drugs is one of the most authentic options to design an adequate treatment for infected patients immediately. In this strategy, Remdesivir (Veklury), Hydroxychloroquine appears to be the drug of choice and garnered unprecedented attention as potential therapeutic agents against the pandemic realized worldwide due to SARS-CoV-2 infection. These are the breathtaking instances of possible repositioning of drugs, whose pharmacokinetics and optimal dosage are familiar. In this review, we provide an overview of these medications, their synthesis, and the possible mechanism of action against SARS-CoV-2.

Identifiers

PMID35942205
PMCPMC9349740
OpenAlexW4285386141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.