Evidence map›Paper›PMID 35942171›Full record

ArticleSmall science2022

Rapid Antigen Diagnostics as Frontline Testing in the COVID-19 Pandemic.

Jiang Xu, Liam Kerr, Yue Jiang, Wenhao Suo, Lei Zhang, Taotao Lao, Yuxin Chen, Yan Zhang

Open access · goldAbstract read
In one paragraph

Article in Small science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Jiang XuDepartment of Systems Biology Blavatnik Institute Harvard Medical School Boston MA 02115 USA.ORCID 0000-0001-7722-8933
Liam KerrDepartment of Mechanical Engineering Center for Intelligent Machines McGill University Montreal QC H3A0C3 Canada.
Yue JiangChina-Australia Institute for Advanced Materials and Manufacturing Jiaxing University Jiaxing 314001 China.
Wenhao SuoDana-Farber Cancer Institute Harvard Medical School Boston MA 02215 USA.
Lei ZhangDepartment of Chemical Engineering Waterloo Institute for Nanotechnology University of Waterloo 200 University Avenue West Waterloo ON N2L3G1 Canada.
Taotao LaoDepartment of Molecular Diagnostics Boston Molecules Inc. 564 Main Street Waltham MA 02452 USA.
Yuxin ChenDepartment of Laboratory Medicine Nanjing Drum Tower Hospital Nanjing University Medical School Nanjing Jiangsu 210008 China.
Yan ZhangTianjin Key Laboratory for Modern Drug Delivery and High-Efficiency Collaborative Innovation Center of Chemical Science and Engineering School of Pharmaceutical Science and Technology Tianjin University Tianjin 300072 China.
Harvard University · USJiaxing University · CNMcGill University · CANanjing Drum Tower Hospital · CNTianjin University · CNUniversity of Waterloo · CA

Funding

Technology Training and Dissemination CoreU54EB027690 · NIBIB · EMORY UNIVERSITY · PI Wilbur A Lam · 2018 to 2026
$96.1M
NIBIB NIH HHS U54 EB027690
6 · The paper itself

Abstract

The ongoing global COVID-19 pandemic, caused by the SARS-CoV-2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the virus and to track the epidemic. Rapid antigen diagnostics has played a significant role in the frontline of COVID-19 testing because of its convenience, low cost, and high accuracy. Herein, different types of recently innovated in-lab and commercial antigen diagnostic technologies with emphasis on the strengths and limitations of these technologies including the limit of detection, sensitivity, specificity, affordability, and usability are systematically reviewed. The perspectives of assay development are looked into.

Indexed as

antigen testsCOVID-19immnuoassaysin vitro diagnostics

Identifiers

PMID35942171
PMCPMC9349911
OpenAlexW4284680289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.