Evidence map›Paper›PMID 35941976›Full record

ArticleBioMed research international2022

Effect of Intervention of Probiotics in Advance on Treg/Th17 in Premature Mice.

Mengmeng Liu, Juanjuan Mao, Shifa Zhang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Subacute exposure to DEHP leads to impaired decidual reaction and exacerbates the risk of early miscarriage in mice.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mengmeng LiuDepartment of Pediatrics, Yijishan Hospital, Wannan Medical College, Wuhu, 241001 Anhui, China.
Juanjuan MaoDepartment of Pediatrics, Yijishan Hospital, Wannan Medical College, Wuhu, 241001 Anhui, China.
Shifa ZhangDepartment of Pediatrics, Yijishan Hospital, Wannan Medical College, Wuhu, 241001 Anhui, China.ORCID https://orcid.org/0000-0002-8102-1318
Wannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To preliminarily understand the differentiation characteristics of regulatory T cells (Tregs) and Th17 at a different time in preterm mice, the impacts of probiotics on immune function progression, as well as the correlation of probiotics with Tregs and Th17. On embryonic day 18 of gestation, a mouse model of preterm birth was built using mifepristone (RU486). Following IPI of RU486, newborn mice were randomized to probiotics or NS gavage administration. Full-term newborn mice were given the same dose of NS gavage administration. Phenotypic analysis of peripheral immune cell frequency was performed using flow cytometry. Cytokine measurements were phenotyped by enzyme-linked immunosorbent assays. On the 14th and 21st days after birth, the highest and lowest expressions of Foxp3, the Treg transcription factor, were observed in full-term mice and premature mice by NS gavage administration, respectively, while the opposite trend was found in the Th17 transcription factor IL-17.IL-2, IL-6, and TGF-

Indexed as

ProbioticsAnimalsAnimals, NewbornCytokinesFemaleInterleukin-2Interleukin-6MiceMifepristoneTh17 CellsT-Lymphocytes, RegulatoryTranscription FactorsTransforming Growth Factor betaCytokinesInterleukin-2Interleukin-6MifepristoneTranscription FactorsTransforming Growth Factor beta

Identifiers

PMID35941976
PMCPMC9356875
OpenAlexW4288872009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.