Evidence map›Paper›PMID 35941934›Full record

ArticleFrontiers in physiology2022

Impact of the Addition of a Centrifugal Pump in a Preterm Miniature Pig Model of the Artificial Placenta.

Alex J Charest-Pekeski, Steven K S Cho, Tanroop Aujla, Liqun Sun, Alejandro A Floh, Mark J McVey, Ayman Sheta, Marvin Estrada, Lynn Crawford-Lean, Celeste Foreman and 11 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Artificial Uterus and Artificial Embryos: Unsolved Tasks.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Review
  5. Artificial womb technology - A more physiologic solution to treating extreme prematurity.European journal of obstetrics & gynecology and reproductive biology: X · 2025
    Review
  6. Reperfused human umbilical cords as anFrontiers in bioengineering and biotechnology · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Advanced imaging of fetal cardiac function.Frontiers in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Alex J Charest-PekeskiDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Steven K S ChoDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Tanroop AujlaDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Liqun SunDivision of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, ON, Canada.
Alejandro A FlohDivision of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, ON, Canada.
Mark J McVeyTranslational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Ayman ShetaDepartment of Pediatrics, Division of Neonatology, The Hospital for Sick Children, Toronto, ON, Canada.
Marvin EstradaLab Animal Services, Peter Gilgan Center for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Lynn Crawford-LeanDivision of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Celeste ForemanDivision of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Dariusz MroczekDivision of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, ON, Canada.
Jaques BelikDepartment of Pediatrics, Division of Neonatology, The Hospital for Sick Children, Toronto, ON, Canada.
Brahmdeep S SainiTranslational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Jessie Mei LimDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Olivia J MoirDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Fu-Tsuen LeeDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Megan QuinnEarly Origins of Adult Health Research Group, Health and Biomedical Innovation, UniSA: Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia.
Jack R T DarbyEarly Origins of Adult Health Research Group, Health and Biomedical Innovation, UniSA: Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia.
Mike SeedDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Janna L MorrisonDepartment of Physiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Christoph HallerDivision of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Hospital for Sick Children · CAUniversity of Toronto · CAUniversity of South Australia · AUSickKids Foundation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent demonstration of normal development of preterm sheep in an artificial extrauterine environment has renewed interest in artificial placenta (AP) systems as a potential treatment strategy for extremely preterm human infants. However, the feasibility of translating this technology to the human preterm infant remains unknown. Here we report the support of 13 preterm fetal pigs delivered at 102 ± 4 days (d) gestation, weighing 616 ± 139 g with a circuit consisting of an oxygenator and a centrifugal pump, comparing these results with our previously reported pumpless circuit (

Indexed as

artificial placentacannulationcentrifugal pumpfetal developmentoxygenatorpreterm pigtachycardia

Identifiers

PMID35941934
PMCPMC9356302
OpenAlexW4286671232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.