ArticleAcademic pathology2022
Validation of portable tablets for transplant pathology diagnosis according to the College of American Pathologists Guidelines.
Article in Academic pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Pilot test for the semi-automated embedding in the pathology laboratory at the University and Hospital Trust of Padua.Virchows Archiv : an international journal of pathology · 2026Article
- Mobile device smartphones for intraoperative diagnosis at the University Hospital Trust of Modena/UNIMORE: from validation process to costs analysis.Diagnostic pathology · 2026Article
- Digital Pathology Displays Under Pressure: Benchmarking Performance Across Market Grades.Journal of imaging informatics in medicine · 2025Article
- Benchmarking digital displays (monitors) for histological diagnoses: the nephropathology use case.Journal of clinical pathology · 2025Article
- AI-algorithm training and validation for identification of endometrial CD138+ cells in infertility-associated conditions; polycystic ovary syndrome (PCOS) and recurrent implantation failure (RIF).Journal of pathology informatics · 2024Article
- Digital pathology structure and deployment in Veneto: a proof-of-concept study.Virchows Archiv : an international journal of pathology · 2024Article
- Cutting-edge technology and automation in the pathology laboratory.Virchows Archiv : an international journal of pathology · 2024Review
- The Puzzle of Preimplantation Kidney Biopsy Decision-Making Process: The Pathologist Perspective.Life (Basel, Switzerland) · 2024Review
- Revolutionizing Cancer Research: The Impact of Artificial Intelligence in Digital Biobanking.Journal of personalized medicine · 2023Review
- Histology for nephrology, from pre-implantation to post-transplant kidney biopsy. Lesson learned from ReBIrth (Renal BIopsy for Kidney Transplantation Therapy).Pathologica · 2023Review
- Horizon of the pre-implantation kidney biopsy for allocation: multidisciplinarity, methodology and innovation.Journal of nephrology · 2023Article
- Second Opinion in the Italian Organ Procurement Transplantation: The Pathologist Is In.Clinics and practice · 2023Article
- Validation of Remote Digital Pathology based diagnostic reporting of Frozen Sections from home.Journal of pathology informatics · 2023Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite increased use of digital pathology, its application in the transplantation setting remains limited. One of the restraints is related to concerns that this technology is inadequate for supporting diagnostic work. In this study, we sought to establish non inferiority of whole slide imaging (WSI) to light microscopy (LM) for intraoperative transplantation diagnosis using inexpensive portable devices. A validation study was conducted according to updated guidelines from the College of American Pathologists (CAP) utilizing 80 intraoperative transplantation cases. Two pathologists reviewed glass slides with LM and digital slides on two different tablets after a washout period of 4 weeks. Diagnostic concordance and intra-observer agreement were recorded. A total of 45 (56%) cases were suitable for rendering transplant diagnoses and 35 (44%) for assessing cancer risk. Intra-observer agreement was 95.1% for organ suitability and 100% for cancer risk. There were no major discordances that could affect patient transplant management. Digital evaluation of intraoperative transplant specimens using tablets to view whole slide images was non-inferior to LM for primary diagnosis. This suggests that after validating WSI these digital tools can be safely used for remote intraoperative transplantation diagnostic work.
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