Evidence map›Paper›PMID 35941552›Full record

ArticleBMC infectious diseases2022

"I am alive because of her": factors affecting adherence to combination antiretroviral therapy among people living with HIV in KwaZulu-Natal, South Africa.

Marian Loveday, Jennifer Furin, Sindisiwe Hlangu, Tasneem Naidoo

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Marian LovedayHIV Prevention Research Unit, South African Medical Research Council, Durban, KwaZulu-Natal, South Africa.
Jennifer FurinDepartment of Global Health and Social Medicine, Harvard Medical School, 641 Huntington Ave., Boston, MA, 02115, USA. jenniferfurin@gmail.com.
Sindisiwe HlanguHIV Prevention Research Unit, South African Medical Research Council, Durban, KwaZulu-Natal, South Africa.
Tasneem NaidooR. K. Khan Hospital HAST Unit, Department of Health, Durban, KwaZulu-Natal, South Africa.
South African Medical Research Council · ZAHarvard University · USR. K. Khan Hospital · ZA

Funding

Bill and Melinda Gates Foundation INV-004597Bill & Melinda Gates Foundation INV-004597
6 · The paper itself

Abstract

backgroundPeople living with HIV need to take lifelong, combination antiretroviral therapy (cART), but there have been only limited explorations of how factors affecting adherence can change over the course of an individual's lifetime.

methodsWe carried out a qualitative study of men and women living with HIV in KwaZulu, Natal, South Africa who were prescribed cART and who had periods of higher and lower adherence.

results18 individuals participated in open-ended interviews. Using a dynamic theory of adherence, we identified factual, relational, and experiential factors that were associated with adherence and non-adherence to cART. Periods of non-adherence were commonly reported. Participants described relationships and experiences as being important influences on their ability to adhere to cART throughout their treatment journeys.

conclusionsPeriods of non-adherence to cART are common. While many cART counseling models are based on conveying facts to people prescribed cART, providing opportunities for supportive relationship where people can process their varied experiences is likely important to maintaining health for people living with HIV.

Indexed as

Antiretroviral Therapy, Highly ActiveHIV InfectionsFemaleHumansMaleMedication AdherenceQualitative ResearchSouth AfricaAdherenceAntiretroviral therapyHIVSouth Africa

Identifiers

PMID35941552
PMCPMC9361592
OpenAlexW4290722763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.