Evidence map›Paper›PMID 35941542›Full record

ArticleBMC pregnancy and childbirth2022

Nomogram prediction for the prediction of clinical pregnancy in Freeze-thawed Embryo Transfer.

Qian Zhang, Xiaolong Wang, Yuming Zhang, Haiou Lu, Yuexin Yu

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qian ZhangDepartment of Reproductive Medicine, General Hospital of Northern Theater Command, Shenhe District, No. 83, Wenhua Road, Shenyang, 110016, China.
Xiaolong WangDepartment of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Yuming ZhangDepartment of Reproductive Medicine, General Hospital of Northern Theater Command, Shenhe District, No. 83, Wenhua Road, Shenyang, 110016, China.
Haiou LuDepartment of Reproductive Medicine, General Hospital of Northern Theater Command, Shenhe District, No. 83, Wenhua Road, Shenyang, 110016, China.
Yuexin YuDepartment of Reproductive Medicine, General Hospital of Northern Theater Command, Shenhe District, No. 83, Wenhua Road, Shenyang, 110016, China. yuyuexinpingan@163.com.

Funding

Key Research and Development Program of Liaoning Province 2020JH2/10300118
6 · The paper itself

Abstract

backgroundThis study aimed to identify multiple endometrial receptivity related factors by applying non-invasive, repeatable multimodal ultrasound methods. Combined with basic clinical data, we further established a practical prediction model for early clinical outcomes in Freeze-thawed Embryo Transfer (FET).

methodsRetrospective analysis of clinical data of infertility patients undergoing FET cycle in our Center from January 2017 to September 2019. Receiver operating characteristic (ROC) curve and decision curve analyses were performed by 500 bootstrap resamplings to assess the determination and clinical value of the nomogram, respectively.

resultsA total of 2457 FET cycles were included. We developed simple nomograms that predict the early clinical outcomes in FET cycles by using the parameters of age, BMI, type and number of embryos transferred, endometrial thickness, FI, RI, PI and number of endometrial and sub-endometrial blood flow. In the training cohort, the area under the ROC curve (AUC) showed statistical accuracy (AUC = 0.698), and similar results were shown in the subsequent validation cohort (AUC = 0.699). Decision curve analysis demonstrated the clinical value of this nomogram.

conclusionsOur nomogram can predict clinical outcomes and it can be used as a simple, affordable and widely implementable tool to provide guidance and treatment recommendations for FET patients.

Indexed as

CryopreservationNomogramsEmbryo TransferEndometriumFemaleHumansPregnancyPregnancy RateRetrospective StudiesClinical pregnancy outcomeEndometrial receptivityFrozen-thawed embryo transferNomogram

Identifiers

PMID35941542
PMCPMC9361510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.