ArticleBMC cardiovascular disorders2022
Relationship between increased systemic immune-inflammation index and coronary slow flow phenomenon.
Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 41 citations in OpenAlex.
- Coronary slow flow: role of systemic inflammation and biomarkers in its pathophysiology.BMC cardiovascular disorders · 2026Article
- Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) Score as a Novel Biomarker for Predicting Coronary Slow Flow in Patients with Angina and/or Ischemia and Nonobstructive Coronary Arteries.Journal of clinical medicine · 2026Article
- Coronary slow flow phenomenon: a meta-analysis of clinical risk predictors.Frontiers in cardiovascular medicine · 2026Review
- Correlation Analysis of the New Inflammatory Composite Index with the Degree of Coronary Artery Lesions in Elderly Patients.Clinical interventions in aging · 2026Article
- Hematological parameters as predictors of complex angiographic coronary lesions in patients with acute myocardial infarction.PloS one · 2026Article
- Association Between Stress Hyperglycemia Ratio and Coronary Slow Flow Phenomenon in Patients with MINOCA.International journal of general medicine · 2026Article
- The Relationship Between Laboratory Parameters and Coronary Slow Flow.Journal of clinical medicine · 2025Article
- Correlation of inflammatory burden index with 30-day readmission rates in patients post-elective percutaneous coronary intervention.Journal of cardiothoracic surgery · 2025Article
- Predictive value of combined inflammatory markers for septic cardiomyopathy: a retrospective study.BMC infectious diseases · 2025Article
- Transcriptome High-Throughput Sequencing Analysis of lncRNA and mRNA Expression in Patients with Coronary Slow Flow.Arquivos brasileiros de cardiologia · 2025Article
- Novel predictive factor for erectile dysfunction: systemic immune inflammation index.International journal of impotence research · 2025Article
- Association between novel Immune-Inflammatory markers and hypertension patients with coronary heart disease: A Cross-Sectional study based on NHANES (2005-2016).BMC cardiovascular disorders · 2025Article
- Comparison of TyG and modified TyG indices in predicting coronary slow flow phenomenon.BMC cardiovascular disorders · 2025Article
- Advanced Lung Cancer Inflammation Index as a Predictor of Coronary Slow Flow Phenomenon in Patients with Angina and Non-Obstructive Coronary Arteries.International journal of general medicine · 2025Article
- The Global Immune-Nutrition Inflammation Index for Predicting Coronary Slow Flow Phenomenon in Patients with Angina and No Obstructive Coronary Arteries.International journal of general medicine · 2025Article
- Coronary Slow-Flow Syndrome: A Review on Natural History of Disease and Best Practices.Research in heart yield and translational medicine · 2025Review
- Functional RNA Applications in Cardiovascular Precision Medicine: Advances and Diagnostic Perspectives.Arquivos brasileiros de cardiologia · 2025Article
- Association Between the Aggregate Index of Systemic Inflammation and Slow Coronary Flow Phenomenon in Patients with Ischemia and No Obstructive Coronary Arteries.International journal of general medicine · 2025Article
- Relationship Between Inflammatory Readings and the Degree of Coronary Atherosclerosis (Pilot Study).Journal of clinical medicine · 2024Article
- Association Between Orthostatic Hypotension With Coronary Slow Flow in Patients With Chest Pain: A Single Center Experience.Clinical cardiology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSystemic immune-inflammation index (SII, platelet × neutrophil/lymphocyte ratio), a new marker of inflammation, is associated with adverse cardiovascular events, but its relationship with coronary slow flow phenomenon (CSFP) is unclear. Therefore, we aimed to investigate the relationship between SII and CSFP.
methodsWe enrolled consecutive patients who presented with chest pain, with normal/near-normal coronary angiography findings (n = 89 as CSFP group; n = 167 as control group). The baseline characteristics, laboratory parameters and angiographic characteristics of the two groups were compared.
resultsSII levels were significantly higher in the CSFP group than in the control group (409.7 ± 17.7 vs. 396.7 ± 12.7, p < 0.001). A significant positive correlation between SII and the mean thrombolysis in myocardial infarction frame count (mTFC) was found (r = 0.624, p < 0.001). SII increased with the number of coronary arteries involved in CSFP. In multivariate logistic regression analysis, SII/10 was an independent predictor of CSFP (odds ratio: 1.739, p < 0.001). In addition, the SII level > 404.29 was a predictor of CSFP with 67.4% sensitivity and 71.9% specificity.
conclusionsSII can predict the occurrence of CSFP.
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