SynthesisNeurocritical care2022
Prognostic Models in Severe Traumatic Brain Injury: A Systematic Review and Meta-analysis.
Synthesis in Neurocritical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Quantitative CT biomarkers for early outcome prediction in acute traumatic brain injury: a systematic review, meta-analysis, and meta-regression.Emergency radiology · 2026Pooled it
- Evaluating and Updating the IMPACT Model to Predict Outcomes in Two Contemporary North American Traumatic Brain Injury Cohorts.Journal of neurotrauma · 2025Trial
- Andexanet alfa Reduces Hematoma Expansion Following Controlled Cortical Impact in Mice Pretreated with Rivaroxaban.Neurocritical care · 2026Article
- Moderate and severe traumatic brain injury: lesion frequency distribution maps and prognostic importance of brain contusions on early MRI.European radiology · 2026Article
- To Do or Not to Do: Decompressive Craniectomy for Severe Traumatic Brain Injury.Asian journal of neurosurgery · 2026Review
- Clinical effect of dexmedetomidine combined with landiolol hydrochloride on cerebral oxygen metabolism and inflammatory response in patients with severe craniocerebral injury.BMC anesthesiology · 2025Article
- Mortality During In-Hospital Stay and the First 24 h After Decompressive Craniectomy in Severe Traumatic Brain Injury: A Multi-Center, Retrospective Propensity Score-Matched Study.Journal of clinical medicine · 2025Article
- Prognostic Factors and Initial Treatment Strategies for Patients with Head Trauma and Vital Signs of Shock.Neurotrauma reports · 2025Article
- Long-Term Functional Recovery after Severe Traumatic Brain Injury with Type II Diffuse Injury.Neurotrauma reports · 2025Article
- Comment on "Comparative Analysis of 'Trauma and Injury Severity Scores' and 'Madras Head Injury Prognostic Scale' in Assessing Head Trauma Prognosis in the Emergency Department of Shahid Beheshti Hospital, Sabzevar, Iran".Bulletin of emergency and trauma · 2025Article
- PaCONeurocritical care · 2024Article
- Assessing outcomes in traumatic brain injury: Helsinki score versus Glasgow coma scale.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- PaCO2 Association with Traumatic Brain Injury Patients Outcomes at High Altitude: A Prospective Single-Center Cohort Study.Research square · 2024Article
- Influencing factors on neurological prognosis after traumatic brain injury and the role of brain tissue oxygen pressure (PbtOAmerican journal of translational research · 2024Article
- An independently validated nomogram for individualised estimation of short-term mortality risk among patients with severe traumatic brain injury: a modelling analysis of the CENTER-TBI China Registry Study.EClinicalMedicine · 2023Article
- Prognostic Value of CRASH and IMPACT Models for Predicting Mortality and Unfavorable Outcome in Traumatic Brain Injury; a Systematic Review and Meta-Analysis.Archives of academic emergency medicine · 2023Review
- Multiple trauma and shock vital signs as potential for improved outcome in patients with severe head trauma.Acute medicine & surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review aimed to analyze the results of investigations that performed external validation or that compared prognostic models to identify the models and their variations that showed the best performance in predicting mortality, survival, and unfavorable outcome after severe traumatic brain injury. Pubmed, Embase, Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature, Google Scholar, TROVE, and Open Grey databases were searched. A total of 1616 studies were identified and screened, and 15 studies were subsequently included for analysis after applying the selection criteria. The Corticosteroid Randomization After Significant Head Injury (CRASH) and International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) models were the most externally validated among studies of severe traumatic brain injury. The results of the review showed that most publications encountered an area under the curve ≥ 0.70. The area under the curve meta-analysis showed similarity between the CRASH and IMPACT models and their variations for predicting mortality and unfavorable outcomes. Calibration results showed that the variations of CRASH and IMPACT models demonstrated adequate calibration in most studies for both outcomes, but without a clear indication of uncertainties in the evaluations of these models. Based on the results of this meta-analysis, the choice of prognostic models for clinical application may depend on the availability of predictors, characteristics of the population, and trauma care services.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.