Evidence map›Paper›PMID 35941401›Full record

ArticleJournal of urban health : bulletin of the New York Academy of Medicine2022

Patient Navigation Can Improve Breast Cancer Outcomes among African American Women in Chicago: Insights from a Modeling Study.

Aditya S Khanna, Bryan Brickman, Michael Cronin, Nyahne Q Bergeron, John R Scheel, Joseph Hibdon, Elizabeth A Calhoun, Karriem S Watson, Shaila M Strayhorn, Yamilé Molina

Registry-linked trialAbstract read
In one paragraph

Article in Journal of urban health : bulletin of the New York Academy of Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07023198 (Provider-Initiated Screening Clinical Breast Examination and Patient Navigation in Sub-Saharan Africa), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07023198 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Provider-Initiated Screening Clinical Breast Examination and Patient Navigation in Sub-Saharan Africa

TypeinterventionalSponsorAddis Ababa UniversityRan2025 to 2027Enrolled8,000ConditionsBreast CancerArmsClinical breast examination and Navigation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Application of patient navigation programs across the entire continuum of breast cancer care: a GRADE-assessed systematic review with meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aditya S KhannaBrown University, Providence, RI, 02912, USA. aditya_khanna@brown.edu.
Bryan BrickmanUniversity of Chicago, Chicago, IL, 60637, USA.
Michael CroninBoston University School of Medicine, Boston, MA, 02118, USA.
Nyahne Q BergeronUniveristy of Illinois Chicago, Chicago, IL, 60607, USA.
John R ScheelUniversity of Washington, Seattle, WA, 98195, USA.
Joseph HibdonNortheastern Illinois University, Chicago, IL, 60625, USA.
Elizabeth A CalhounUniversity of Kansas, Lawrence, KS, 66045, USA.
Karriem S WatsonNational Institutes of Health, Bethesda, MD, 20814, USA.
Shaila M StrayhornUniversity of North Carolina Wilmington, Wilmington, NC, 28403, USA.
Yamilé MolinaUniveristy of Illinois Chicago, Chicago, IL, 60607, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
Using wearables and EMA to examine the links between cannabis and depressionP20GM130414 · NIGMS · BROWN UNIVERSITY · PI Jasjit Singh Ahluwalia · 2019 to 2026
$22.0M
Cancer Health Equity Career Development ProgramT32CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Marian L. Fitzgibbon · 2018 to 2026
$3.0M
NU-STARS for Northeastern Illinois Student Training in Academic Research in the SciencesT34GM105549 · NIGMS · NORTHEASTERN ILLINOIS UNIVERSITY · PI CHURCH, RUTH B, HIBDON, JOSEPH EDWARD · 2014 to 2023
$2.8M
Assessing and modeling network-level consequences of patient navigationR21CA215252 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KHANNA, ADITYA SUBHASH, MOLINA, YAMILE · 2018 to 2019
$401k
NCI NIH HHS R21 CA 215252NCI NIH HHS R21 CA215252NCI NIH HHS T32 CA 057699NCI NIH HHS T32 CA057699NIAID NIH HHS P30 AI042853NIGMS NIH HHS P20 GM 130414.NIGMS NIH HHS P20 GM130414NIGMS NIH HHS T34 GM105549
6 · The paper itself

Abstract

African American (AA) women experience much greater mortality due to breast cancer (BC) than non-Latino Whites (NLW). Clinical patient navigation is an evidence-based strategy used by healthcare institutions to improve AA women's breast cancer outcomes. While empirical research has demonstrated the potential effect of navigation interventions for individuals, the population-level impact of navigation on screening, diagnostic completion, and stage at diagnosis has not been assessed. An agent-based model (ABM), representing 50-74-year-old AA women and parameterized with locally sourced data from Chicago, is developed to simulate screening mammography, diagnostic resolution, and stage at diagnosis of cancer. The ABM simulated three counterfactual scenarios: (1) a control setting without any navigation that represents the "standard of care"; (2) a clinical navigation scenario, where agents receive navigation from hospital-affiliated staff; and (3) a setting with network navigation, where agents receive clinical navigation and/or social network navigation (i.e., receiving support from clinically navigated agents for breast cancer care). In the control setting, the mean population-level screening mammography rate was 46.3% (95% CI: 46.2%, 46.4%), the diagnostic completion rate was 80.2% (95% CI: 79.9%, 80.5%), and the mean early cancer diagnosis rate was 65.9% (95% CI: 65.1%, 66.7%). Simulation results suggest that network navigation may lead up to a 13% increase in screening completion rate, 7.8% increase in diagnostic resolution rate, and a 4.9% increase in early-stage diagnoses at the population-level. Results suggest that systems science methods can be useful in the adoption of clinical and network navigation policies to reduce breast cancer disparities.

Indexed as

Breast NeoplasmsPatient NavigationAgedBlack or African AmericanChicagoEarly Detection of CancerFemaleHumansMammographyMiddle AgedAfrican AmericansBreast cancer screeningComputer simulationEarly diagnosisPreventive medicine

Identifiers

PMID35941401
PMCPMC9561367

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.