ArticleClinical oral investigations2023
Salivary film thickness and MUC5B levels at various intra-oral surfaces.
Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 23 citations in OpenAlex.
- Dose-Dependent Protective Effects of Agmatine on Sublingual Gland Dysfunction and Pancreatic Damage in Experimental Diabetes: Evidence From Histological, Biochemical, and Immunohistochemical Analyses.Microscopy research and technique · 2026Article
- AMY1 gene copy number associated with xerostomia and Sjögren's syndrome: a cross-sectional study.BMC oral health · 2025Article
- Short-term effects of sweetened acidic beverages consumption on human saliva: Colloidal properties and protein composition.PloS one · 2025Article
- Exploring the role of the MUC1 mucin in human oral lubrication by tribological in vitro studies.Scientific reports · 2024Article
- A first-of-its-kind 3D biomimetic artificial mouth capable of reproducing the oral processing of soft foods.Scientific reports · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesIn this study, we investigated the salivary film thickness and the MUC5B levels at various intra-oral locations in healthy volunteers, with a focus on the palate. Besides, measurements of the palatal surface area were included to explore the possible relationships between the palatal surface area and the palatal salivary film and MUC5B levels. MATERIALS AND
methodsThe salivary film thickness was determined using filter strips, which were pressed to the mucosal surfaces of five different intra-oral locations; conductance was then analysed using a Periotron. After elution of the strips, the MUC5B levels at various intra-oral locations were determined using ELISA. The palatal surface area was measured using an intra-oral scanner. The surface area was subsequently calculated using the software.
resultsThe anterior tongue had the thickest salivary film and also the highest levels of MUC5B, while the anterior palate had the thinnest salivary film and lowest MUC5B levels. There was no association between the palatal surface area and the salivary film thickness of the palate.
conclusionThe salivary film and MUC5B levels are unequally distributed over the intra-oral regions of the soft tissues. The lack of association between the palatal surface area and the salivary film thickness indicates that a larger surface area is not associated with a relative thinner palatal salivary film. CLINICAL RELEVANCE: The results of the current study increase our understanding of saliva distribution in the oral cavity and could be used as reference values for future studies.
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