Evidence map›Paper›PMID 35941339›Full record

ArticleClinical rheumatology2022

Clinical analysis of 99 children with Henoch-Schönlein purpura complicated with overt gastrointestinal bleeding.

Yang Yang, Jing Shu, Jing Mu, Qiang He, Fang Chen, Yan Hu, Xiaofang Zhen

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yang YangDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China.
Jing ShuDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China.
Jing MuDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China.
Qiang HeDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China.
Fang ChenDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China.
Yan HuDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China.
Xiaofang ZhenDepartment of Traditional Chinese Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China, Beijing, 100045, China. zhenxiaofang2007@sina.com.ORCID http://orcid.org/0000-0001-8781-9999
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze and summarize the clinical features, diagnosis, and treatment of children with Henoch-Schönlein purpura (HSP) complicated by overt gastrointestinal bleeding (GI bleeding) for achieving early identification, prevention, and treatment in terms of severe GI bleeding.

methodsA retrospective analysis was conducted on children with HSP complicated by overt GI bleeding who were admitted to the Department of Traditional Chinese Medicine of Beijing Children's Hospital from January 2017 to December 2019. According to the severity of GI bleeding, the patients were divided into mild bleeding group (61 cases) and moderate and severe bleeding group (38 cases). Inflammatory parameters, coagulation function, GI ultrasound findings, and clinical features were compared. Logistic regression analysis was used to determine the related variables affecting the severity of GI bleeding, and the ROC curve was used to determine the variable test efficacy.

resultsOnset in summer, wide distribution of skin rash with facial involvement, the elevation of D-dimer and high neutrophil-to-lymphocyte ratio (NLR) had significant effects on the severity of GI bleeding. ROC curve analysis showed that the optimal cut-off points of NLR and D-dimer for predicting severe GI bleeding in children with HSP were 10.56 and 0.89 mg/L, respectively.

conclusionFacial rash may be a warning sign of GI bleeding. Enhanced monitoring of NLR and D-dimer is helpful for early recognition of GI bleeding as well as assessment of severity.

Indexed as

IgA VasculitisChildGastrointestinal HemorrhageHumansLymphocytesNeutrophilsRetrospective StudiesD-dimerGastrointestinal bleedingHenoch-Schönlein purpuraNLR

Identifiers

PMID35941339
OpenAlexW4292292466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.