Evidence map›Paper›PMID 35941193›Full record

Observational studyScientific reports2022

Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru.

Jorge Honles, Claire Clisson, Claudia Monge, Pedro Vásquez-Ocmín, Juan Pablo Cerapio, Sysay Palamy, Sandro Casavilca-Zambrano, Javier Herrera, Pascal Pineau, Eric Deharo and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jorge Honles *UMR 152 PHARMADEV, IRD, UPS, Université de Toulouse, Toulouse, France.
Claire Clisson *Institut de Recherche et d'Expertise Scientifique, Europarc, Strasbourg, France.
Claudia MongeUMR 152 PHARMADEV, IRD, UPS, Université de Toulouse, Toulouse, France.
Pedro Vásquez-OcmínUMR 152 PHARMADEV, IRD, UPS, Université de Toulouse, Toulouse, France.
Juan Pablo CerapioInternational Joint Laboratory of Molecular Anthropological Oncology (LOAM), IRD, INEN, Lima, Peru.
Sysay PalamyFaculty of Pharmacy, University of Health Sciences, Vientiane, Laos.
Sandro Casavilca-ZambranoInternational Joint Laboratory of Molecular Anthropological Oncology (LOAM), IRD, INEN, Lima, Peru.
Javier HerreraUMR 260 LEDa, IRD, CNRS UMR 8007-260, Université Paris Dauphine, Paris, France.
Pascal PineauUnité Organisation Nucléaire et Oncogenèse, Institut Pasteur, INSERM U 993, Paris, France.
Eric DeharoUMR 224 MIVEGEC, IRD, CNRS UMR 5290, Université de Montpellier, Montpellier, France.
Vincent PeynetInstitut de Recherche et d'Expertise Scientifique, Europarc, Strasbourg, France.
Stéphane BertaniUMR 152 PHARMADEV, IRD, UPS, Université de Toulouse, Toulouse, France. stephane.bertani@ird.fr.

Funding

Marie Curie 823935
6 · The paper itself

Abstract

The Central Andes of Peru are a region of great concern regarding pesticide risk to the health of local communities. Therefore, we conducted an observational study to assess the level of pesticide contamination among Andean people. Analytical chemistry methods were used to measure the concentrations of 170 pesticide-related compounds in hair samples from 50 adult Andean subjects living in rural and urban areas. As part of the study, a questionnaire was administered to the subjects to collect information regarding factors that increase the risk of pesticide exposure. Our results indicate that Andean people are strongly exposed to agrochemicals, being contaminated with a wide array of pesticide-related compounds at high concentration levels. Multivariate analyses and geostatistical modeling identified sociodemographic factors associated with rurality and food origin that increase pesticide exposure risk. The present study represents the first comprehensive investigation of pesticide-related compounds detected in body samples collected from people living in the Central Andes of Peru. Our findings pinpoint an alarming environmental situation that threatens human health in the region and provide a rationale for improving public policies to protect local communities.

Indexed as

PesticidesAdultAgrochemicalsEnvironmental ExposureHumansPeruAgrochemicalsPesticides

Identifiers

PMID35941193
PMCPMC9360020

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.