ArticleScientific reports2022
Exploring the medicinally important secondary metabolites landscape through the lens of transcriptome data in fenugreek (Trigonella foenum graecum L.).
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 29 citations in OpenAlex.
- Identification of candidate genes governing key metabolic pathways in fenugreek (Trigonella spp.) through integrated transcriptomic and metabolomic analysis.Functional & integrative genomics · 2026Article
- LC-MS/MS-Based Comparative Phytochemical Profiling and Multivariate (PCA) Analysis of Seed Extracts fromInternational journal of molecular sciences · 2026Article
- Chromosome-scale genome assembly of Trigonella corniculata (L.)L. (Nagauri pan /Kasuri methi), an important spice.Scientific data · 2025Article
- GRAYU: graph-based database integrating Ayurvedic formulations, medicinal plants, phytochemicals and diseases.Frontiers in pharmacology · 2025Article
- Tissue-specific biosynthesis and regulation of alkaloids, flavonoids, and terpenoids in fenugreek (Frontiers in plant science · 2025Article
- Characterization of bioactive compounds in fenugreek genotypes in varying environments: diosgenin, trigonelline, and 4-hydroxyisoleucine.Frontiers in plant science · 2025Article
- Formulation and assessment of chickpea pulao using fenugreek seeds and Indian rennet to improve blood glycemic levels.Food science & nutrition · 2024Article
- Transcriptomic data reveals the dynamics of terpenoids biosynthetic pathway of fenugreek.BMC genomics · 2024Article
- Variability in genome size of Trigonella foenum-graecum, Trigonella corniculata and Trigonella caerulea as estimated by flow cytometry indicates complex evolutionary history of fenugreek.Molecular biology reports · 2024Article
- Article
- Genome-Wide Comparative Profiles of Triterpenoid Biosynthesis Genes in Ginseng and Pseudo Ginseng Medicinal Plants.Life (Basel, Switzerland) · 2023Article
- Multivariate analysis of seed chemical diversity among wild fenugreek (Trigonella monantha C. A. Mey.) ecotypes.BMC plant biology · 2023Article
- Integration of high-throughput omics technologies in medicinal plant research: The new era of natural drug discovery.Frontiers in plant science · 2023Review
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15 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Fenugreek (Trigonella foenum-graecum L.) is a self-pollinated leguminous crop belonging to the Fabaceae family. It is a multipurpose crop used as herb, spice, vegetable and forage. It is a traditional medicinal plant in India attributed with several nutritional and medicinal properties including antidiabetic and anticancer. We have performed a combined transcriptome assembly from RNA sequencing data derived from leaf, stem and root tissues. Around 209,831 transcripts were deciphered from the assembly of 92% completeness and an N50 of 1382 bases. Whilst secondary metabolites of medicinal value, such as trigonelline, diosgenin, 4-hydroxyisoleucine and quercetin, are distributed in several tissues, we report transcripts that bear sequence signatures of enzymes involved in the biosynthesis of such metabolites and are highly expressed in leaves, stem and roots. One of the antidiabetic alkaloid, trigonelline and its biosynthesising enzyme, is highly abundant in leaves. These findings are of value to nutritional and the pharmaceutical industry.
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