Evidence map›Paper›PMID 35941168›Full record

ArticleNature communications2022

Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size.

Runfeng Miao, Harim Chun, Xing Feng, Ana Cordeiro Gomes, Jungmin Choi, João P Pereira

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Runfeng MiaoDepartment of Immunobiology and Yale Stem Cell Center, Yale University School of Medicine, 300 Cedar Street, New Haven, CT, 06519, USA.
Harim ChunBK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, 02841, Republic of Korea.
Xing FengDepartment of Immunobiology and Yale Stem Cell Center, Yale University School of Medicine, 300 Cedar Street, New Haven, CT, 06519, USA.
Ana Cordeiro GomesDepartment of Immunobiology and Yale Stem Cell Center, Yale University School of Medicine, 300 Cedar Street, New Haven, CT, 06519, USA.
Jungmin ChoiBK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul, 02841, Republic of Korea. jungmin.choi@yale.edu.ORCID 0000-0002-8614-0973
João P PereiraDepartment of Immunobiology and Yale Stem Cell Center, Yale University School of Medicine, 300 Cedar Street, New Haven, CT, 06519, USA. joao.pereira@yale.edu.ORCID 0000-0002-5694-4938
Yale Cancer Center · USKorea University · KR

Funding

Cellular and molecular analysis of B lymphocyte development and selectionR01AI113040 · NIAID · YALE UNIVERSITY · PI JOAO PEREIRA · 2014 to 2026
$6.0M
Mechanisms of peripheral B cell differentiation and homeostasisR21AI133060 · NIAID · YALE UNIVERSITY · PI PEREIRA, JOAO · 2018 to 2019
$461k
NIAID NIH HHS R01 AI113040NIAID NIH HHS R21 AI133060
6 · The paper itself

Abstract

Cellular competition for limiting hematopoietic factors is a physiologically regulated but poorly understood process. Here, we studied this phenomenon by hampering hematopoietic progenitor access to Leptin receptor

Indexed as

Endothelial CellsMesenchymal Stem CellsCell DifferentiationHematopoietic Stem CellsStem Cell FactorStem Cell Factor

Identifiers

PMID35941168
PMCPMC9360400
OpenAlexW4290702149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.