Evidence map›Paper›PMID 35941116›Full record

ArticleNature communications2022

Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis.

Elle Koren, Alona Feldman, Marianna Yusupova, Avihay Kadosh, Egor Sedov, Roi Ankawa, Yahav Yosefzon, Waseem Nasser, Stefanie Gerstberger, Liam B Kimel and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Cell proliferation and differentiation during epidermis renewal.Journal of Zhejiang University. Science. B · 2026
    Review
  3. Article
  4. Article
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  7. Article
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  11. Article
  12. Review
  13. Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Elle Koren *Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Alona Feldman *Laboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Marianna YusupovaLaboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Avihay KadoshLaboratory of Biophysics, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Egor SedovLaboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Roi AnkawaLaboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Yahav YosefzonLaboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Waseem NasserDepartment of Genetics and Developmental Biology, The Rappaport Faculty of Medicine and Research Institute, Technion Israel Institute of Technology, Haifa, Israel.
Stefanie GerstbergerMassachusetts General Hospital, Boston, CA, USA.
Liam B KimelLaboratory of Biophysics, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Noa PriselacLaboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel.
Samara BrownStrang Laboratory of Apoptosis and Cancer Biology, The Rockefeller University, New York, New York, 10065, USA.
Sam SharmaStrang Laboratory of Apoptosis and Cancer Biology, The Rockefeller University, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0003-4590-0128
Travis GorencStrang Laboratory of Apoptosis and Cancer Biology, The Rockefeller University, New York, New York, 10065, USA.
Ruby Shalom-FeuersteinDepartment of Genetics and Developmental Biology, The Rappaport Faculty of Medicine and Research Institute, Technion Israel Institute of Technology, Haifa, Israel.
Hermann StellerStrang Laboratory of Apoptosis and Cancer Biology, The Rockefeller University, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0002-4577-4507
Tom ShemeshLaboratory of Biophysics, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel. tomsh@technion.ac.il.ORCID http://orcid.org/0000-0003-4318-6258
Yaron FuchsLaboratory of Stem Cell Biology and Regenerative Medicine, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel. yfuchs@technion.ac.il.ORCID http://orcid.org/0000-0003-4391-9386
Technion – Israel Institute of Technology · ILRockefeller University · USMassachusetts General Hospital · US

Funding

Proteasome Regulation and Function in Cellular RemodelingR01GM060124 · NIGMS · ROCKEFELLER UNIVERSITY · PI STELLER, HERMANN · 1999 to 2018
$5.4M
NIGMS NIH HHS R01 GM060124
6 · The paper itself

Abstract

The presence of distinct stem cells that maintain the interfollicular epidermis is highly debated. Here, we report a population of keratinocytes, marked by Thy1, in the basal layer of the interfollicular epidermis. We find that epidermal cells expressing differential levels of Thy1 display distinct transcriptional signatures. Thy1

Indexed as

Epidermal CellsStem CellsAnimalsCell DifferentiationEpidermisKeratinocytesMice

Identifiers

PMID35941116
PMCPMC9360001
OpenAlexW4294991362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.