Evidence map›Paper›PMID 35941112›Full record

ArticleNature communications2022

Acetate reprograms gut microbiota during alcohol consumption.

Cameron Martino, Livia S Zaramela, Bei Gao, Mallory Embree, Janna Tarasova, Seth J Parker, Yanhan Wang, Huikuan Chu, Peng Chen, Kuei-Chuan Lee and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 90 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Precision pathophysiology in steatotic liver disease.Clinical and molecular hepatology · 2026
    Review
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  7. Article
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  19. Endogenous Ethanol Metabolism and Development of MASLD-MASH.International journal of molecular sciences · 2025
    Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Cameron Martino *Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9334-1258
Livia S Zaramela *Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-1065-3799
Bei Gao *Department of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-3321-2339
Mallory EmbreeDepartment of Bioengineering, University of California, San Diego, CA, USA.
Janna TarasovaDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Seth J ParkerDepartment of Bioengineering, University of California, San Diego, CA, USA.ORCID 0000-0001-7971-8848
Yanhan WangDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Huikuan ChuDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Peng ChenDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Kuei-Chuan LeeDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Daniela Domingos GalzeraniDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Jivani M GengatharanDepartment of Bioengineering, University of California, San Diego, CA, USA.
Asama LekbuaDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Maxwell NealDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Rob KnightDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-0975-9019
Hidekazu TsukamotoSouthern California Research Center for ALPD and Cirrhosis and Department of Pathology, La Jolla, CA, USA.
Christian M MetalloDepartment of Bioengineering, University of California, San Diego, CA, USA.
Bernd SchnablCenter for Microbiome Innovation, University of California San Diego, La Jolla, CA, USA. beschnabl@health.ucsd.edu.
Karsten ZenglerDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA. kzengler@ucsd.edu.ORCID 0000-0002-8062-3296
University of California San Diego · USSalk Institute for Biological Studies · USSouthern California Reproductive Center · USUC San Diego Health System · US

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8M
The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ANNA S. GUKOVSKAYA · 1999 to 2026
$45.8M
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LARS ECKMANN, Bernd G. Schnabl · 2019 to 2026
$10.8M
The Role of the Intestinal Mycobiome in Alcoholic Liver DiseaseR01AA024726 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2018 to 2026
$3.9M
Microbiome and Intestinal Innate Immune Response in Alcoholic Liver DiseaseR37AA020703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2021 to 2026
$2.5M
Non-essential amino acids and sphingolipid diversity in cancer progressionR01CA234245 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI METALLO, CHRISTIAN MICHAEL · 2019 to 2023
$1.9M
Microbiome as therapeutic target in alcoholic hepatitisU01AA026939 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FOUTS, DERRICK E, SCHNABL, BERND G. · 2018 to 2022
$1.7M
BLRD VA I01 BX001991BLRD VA I01 BX004594BLRD VA IK6 BX004205NCI NIH HHS P30 CA014195NCI NIH HHS R01 CA234245NIAAA NIH HHS P50 AA011999NIAAA NIH HHS R01 AA024726NIAAA NIH HHS R37 AA020703NIAAA NIH HHS U01 AA026939NIDDK NIH HHS P30 DK120515
6 · The paper itself

Abstract

Liver damage due to chronic alcohol use is among the most prevalent liver diseases. Alcohol consumption frequency is a strong factor of microbiota variance. Here we use isotope labeled [1-

Indexed as

Gastrointestinal MicrobiomeLiver DiseasesAcetatesAlcohol DrinkingAnimalsEthanolMiceMice, Inbred C57BLAcetatesEthanol

Identifiers

PMID35941112
PMCPMC9359997
OpenAlexW4291020874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.