Evidence map›Paper›PMID 35940907›Full record

ReviewCold Spring Harbor perspectives in biology2023

Regulation and Functions of the ER-Associated Nrf1 Transcription Factor.

Gary Ruvkun, Nicolas Lehrbach

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Subcellular localization as a driver of protein function.Nature reviews. Molecular cell biology · 2026
    Review
  6. Review
  7. Review
  8. NFE2L1/Nrf1 forms a coactivator complex post-peptide:Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
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  18. Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gary RuvkunDepartment of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Simches Research Building, Boston, MA 02114, USA.
Nicolas LehrbachBasic Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA.
Fred Hutch Cancer Center · USMassachusetts General Hospital · US

Funding

GENETIC AND MOLECULAR BASIS OF LONGEVITYR01AG016636 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI GARY B RUVKUN · 1999 to 2026
$12.4M
Regulation of Proteasome CapacityR35GM142728 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LEHRBACH, NICOLAS JOHN · 2021 to 2025
$2.3M
NIA NIH HHS R01 AG016636NIGMS NIH HHS R35 GM142728
6 · The paper itself

Abstract

Nrf1 is a member of the nuclear erythroid 2-like family of transcription factors that regulate stress-responsive gene expression in animals. Newly synthesized Nrf1 is targeted to the endoplasmic reticulum (ER) where it is

Indexed as

Nuclear Respiratory Factor 1Proteasome Endopeptidase ComplexAnimalsEndoplasmic ReticulumGene Expression RegulationProteolysisTranscription FactorsNuclear Respiratory Factor 1Proteasome Endopeptidase ComplexTranscription Factors

Identifiers

PMID35940907
PMCPMC9808582
OpenAlexW4292283940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.